Difference between revisions of "Cholecystitis"
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==Microscopic evaluation== | ==Microscopic evaluation== | ||
+ | Classify cholecystitis as acute, chronic or both acute and chronic. | ||
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===Findings in '''acute''' cholecystisis=== | ===Findings in '''acute''' cholecystisis=== | ||
Main initial features are '''edema''' and '''hemorrhage'''.<ref name=Mills>{{cite book |author= Mills, Stacey E; Carter, Darryl; Greenson, Joel K; Reuter, Victor E; Stoler, Mark H |title=Sternberg's Diagnostic Surgical Pathology |publisher=Lippincott Williams & Wilkins |location= |year=2009 |pages=|edition=5th |isbn=978-0781779425 |oclc= |doi= |accessdate=}}</ref> | Main initial features are '''edema''' and '''hemorrhage'''.<ref name=Mills>{{cite book |author= Mills, Stacey E; Carter, Darryl; Greenson, Joel K; Reuter, Victor E; Stoler, Mark H |title=Sternberg's Diagnostic Surgical Pathology |publisher=Lippincott Williams & Wilkins |location= |year=2009 |pages=|edition=5th |isbn=978-0781779425 |oclc= |doi= |accessdate=}}</ref> |
Revision as of 17:12, 9 September 2020
Author:
Mikael Häggström [note 1]
Inflammation of the gallbladder:
Contents
Gross processing
As per basic Gallbladder.
Microscopic evaluation
Classify cholecystitis as acute, chronic or both acute and chronic.
Findings in acute cholecystisis
Main initial features are edema and hemorrhage.[1]
- Initially often also congestion and fibrin deposition in and around the muscular layer.[2]
- Later often necrosis of the mucosa and and deeper layers, with neutrophils.[2]
- Variable reactive epithelial changes, which may resemble dysplasia.[2]
There may be fresh thrombi within small veins.[2]
Findings in chronic cholecystitis
Typical features are:[3]
- Smooth muscle hypertrophy in the muscularis
- Mild inflammatory infiltrates
- Rokitansky-Aschoff sinuses
Other findings favoring the diagnosis are:[3]
- Granulomas (from ruptured Rokitansky-Aschoff sinuses) strogly favor the diagnosis.
- Hyalinized collagen
- Dystrophic calcification
- Lymphoid aggregates
- Atrophic and/or ulcerated mucosa
- Metaplastic changes, such as gastric or intestinal mucosa
For a general gallbladder screening, see gallbladder.
Lymph nodes
Look for reactive lymphadenopathy or metastasis. Further information: Lymph node
Notes
- ↑ For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.
Main page
References
- ↑ Mills, Stacey E; Carter, Darryl; Greenson, Joel K; Reuter, Victor E; Stoler, Mark H (2009). Sternberg's Diagnostic Surgical Pathology (5th ed.). Lippincott Williams & Wilkins. ISBN 978-0781779425.
- ↑ 2.0 2.1 2.2 2.3 Hanni Gulwani. Gallbladder & extrahepatic bile ducts - Cholecystitis. Pathology Outlines. Topic Completed: 1 September 2012. Minor changes: 5 September 2019
- ↑ 3.0 3.1 Hanni Gulwani. Gallbladder - Cholecystitis - Chronic cholecystitis. Topic Completed: 1 September 2012. Revised: 9 January 2020
Image sources