Chronic appendicitis

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Author: Mikael Häggström [note 1]
Chronic appendicitis:


Generally 10% neutral buffered formalin.

  See also: General notes on fixation

Gross processing

Further information: Appendix A major clue to chronic appendicitis is fibrosis.[1]

Microscopic evaluation

Patchy chronic peri-appendicitis.

Further information: Appendicitis Chronic appendicitis has predominantly mononuclear infiltrate rather than neutrophilic.[1] It must go beyond the normal histological locations of mononuclear leucocytes of the appendix.

Even when chronic appendicitis is detected, also look for acute appendicitis, as well as appendix cancer (Further information: Appendix )

Microscopy report


Histopathology of patchy chronic peri-appendicitis.jpg
Patchy chronic peri-appendicitis. Negative for suppurative inflammation.


  1. For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.

Main page


  1. 1.0 1.1 Sierakowski, Kyra; Pattichis, Andrew; Russell, Patrick; Wattchow, David (2016). "Unusual presentation of a familiar pathology: chronic appendicitis ". BMJ Case Reports: bcr2015212485. doi:10.1136/bcr-2015-212485. ISSN 1757-790X. 

Image sources