Difference between revisions of "Donor kidney biopsy"
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==Microscopic evaluation== | ==Microscopic evaluation== | ||
Generally evaluate as per local protocol, which may include the following, given individually for right and left kidney: | Generally evaluate as per local protocol, which may include the following, given individually for right and left kidney: | ||
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File:Total hyalinization of a glomerulus.jpg|- '''Number''' of glomeruli with '''global sclerosis'''<br>- Total '''number of glomeruli'''.<br>- '''Percentage''' of glomeruli with '''global sclerosis''' (number of glomeruli with global sclerosis divided by total number of glomeruli). | File:Total hyalinization of a glomerulus.jpg|- '''Number''' of glomeruli with '''global sclerosis'''<br>- Total '''number of glomeruli'''.<br>- '''Percentage''' of glomeruli with '''global sclerosis''' (number of glomeruli with global sclerosis divided by total number of glomeruli). | ||
File:Histopathology of tubular atrophy.png|'''Tubular atrophy'''/'''tubular interstitial fibrosis''', as percentage of tubules. Features of tubular atrophy are shown.<ref>{{cite journal| author=Schelling JR| title=Tubular atrophy in the pathogenesis of chronic kidney disease progression. | journal=Pediatr Nephrol | year= 2016 | volume= 31 | issue= 5 | pages= 693-706 | pmid=26208584 | doi=10.1007/s00467-015-3169-4 | pmc=4726480 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26208584 }} </ref>{{MH}} | File:Histopathology of tubular atrophy.png|'''Tubular atrophy'''/'''tubular interstitial fibrosis''', as percentage of tubules. Features of tubular atrophy are shown.<ref>{{cite journal| author=Schelling JR| title=Tubular atrophy in the pathogenesis of chronic kidney disease progression. | journal=Pediatr Nephrol | year= 2016 | volume= 31 | issue= 5 | pages= 693-706 | pmid=26208584 | doi=10.1007/s00467-015-3169-4 | pmc=4726480 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26208584 }} </ref>{{MH}} | ||
Revision as of 14:12, 17 May 2022
Author:
Mikael Häggström [note 1]
Memorization-worthy:[note 2] A donor kidney biopsy may come for frozen sectioning.
Contents
Gross processing
Prepare a separate slide for right versus left kidney if applicable.
Microscopic evaluation
Generally evaluate as per local protocol, which may include the following, given individually for right and left kidney:
- Number of glomeruli with global sclerosis
- Total number of glomeruli.
- Percentage of glomeruli with global sclerosis (number of glomeruli with global sclerosis divided by total number of glomeruli).
Arteriosclerosis seen as intimal thickening with an onion skin-like appearance. Arteriosclerosis can be graded as mild, moderate or severe.
Arteriolar hyalinosis
Notes
- ↑ For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.
- ↑ Further information on what is memorization-worthy or not: Learning pathology
Main page
References
- ↑ Schelling JR (2016). "Tubular atrophy in the pathogenesis of chronic kidney disease progression. ". Pediatr Nephrol 31 (5): 693-706. doi:. PMID 26208584. PMC: 4726480. Archived from the original. .
Image sources
- ↑ Image(s) by: Mikael Häggström, M.D. Public Domain
- Author info
- Reusing images
