Elastosis
Author:
Mikael Häggström [note 1]
Elastosis is the buildup of elastin in tissues, and is a form of degenerative disease.[1]
Contents
Fixation and gross processing
See skin.
Microscopic evaluation
Consider the main causes of elastosis:
Condition | Distinctive features | Histopathology |
---|---|---|
Actinic elastosis (most common, also called solar elastosis) |
Elastin replacing collagen fibers of the papillary dermis and reticular dermis. Often, solar elastosis is found incidentally with other lesions. |
|
Elastosis perforans serpiginosa | Degenerated elastic fibers and transepidermal perforating canals (arrow in image points at one of them)[2] | |
Perforating calcific elastosis] | Clumping of short elastic fibers in the dermis.[2] | |
Linear focal elastosis | Accumulation of fragmented elastotic material within the papillary dermis and transcutaneous elimination of elastotic fibers.[2] |
Incidentally discovered elastosis in skin that may have received prolonged sun-exposure can be presumed to be solar elastosis if there are no characteristics of any differential diagnosis thereof.
Reporting
- The presence of elastosis, with the most probable cause thereof.
In incidentally discovered solar elastosis in case of another disease, description may be brief, such as "Solar elastosis (optionally:, also in surrounding skin)."
See also: General notes on reporting
Notes
- ↑ For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.
Main page
References
- ↑ Beth Wright. Elastosis. DermNet NZ.
- ↑ 2.0 2.1 2.2 Hosen, Mohammad J.; Lamoen, Anouck; De Paepe, Anne; Vanakker, Olivier M. (2012). "Histopathology of Pseudoxanthoma Elasticum and Related Disorders: Histological Hallmarks and Diagnostic Clues
". Scientifica 2012: 1–15. doi: . ISSN 2090-908X.
-Creative Commons Attribution 3.0 Unported license
Image sources