Difference between revisions of "Endometrial polyp"

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[[File:Endometrial histopathologies and cytopathologies.jpg|thumb|420px|Histopathologic and cytopathologic images.<br>(A) '''proliferative''' endometrium (Left: HE × 400) and proliferative endometrial cells (Right: HE × 100)<br>(B) '''secretory''' endometrium (Left: HE × 10) and secretory endometrial cells (Right: HE × 10)<br>(C) '''atrophic''' endometrium (Left: HE × 10) and atrophic endometrial cells (Right: HE × 10)<br>(D) '''mixed''' endometrium (Left: HE × 10) and mixed endometrial cells (Right: HE × 10)<br>(E): endometrial '''atypical hyperplasia''' (Left: HE × 10) and endometrial atypical cells (Right: HE × 200)<br>(F) '''endometrial carcinoma''' (Left: HE × 400) and endometrial cancer cells (Right: HE × 400).]]
 
[[File:Endometrial histopathologies and cytopathologies.jpg|thumb|420px|Histopathologic and cytopathologic images.<br>(A) '''proliferative''' endometrium (Left: HE × 400) and proliferative endometrial cells (Right: HE × 100)<br>(B) '''secretory''' endometrium (Left: HE × 10) and secretory endometrial cells (Right: HE × 10)<br>(C) '''atrophic''' endometrium (Left: HE × 10) and atrophic endometrial cells (Right: HE × 10)<br>(D) '''mixed''' endometrium (Left: HE × 10) and mixed endometrial cells (Right: HE × 10)<br>(E): endometrial '''atypical hyperplasia''' (Left: HE × 10) and endometrial atypical cells (Right: HE × 200)<br>(F) '''endometrial carcinoma''' (Left: HE × 400) and endometrial cancer cells (Right: HE × 400).]]
 
The main objectives are:
 
The main objectives are:
*Confirm an endometrioid polyp. An endometrial polyp may be diagnosed in the presence of 2 of the following 3:
+
*Making a '''diagnosis''' of endometrioid polyp. An endometrial polyp may be diagnosed in the presence of 2 of the following 3:
 
:*Thick-walled vessels
 
:*Thick-walled vessels
 
:*Collagenous stroma
 
:*Collagenous stroma
 
:*Epithelium on at least 3 sides
 
:*Epithelium on at least 3 sides
*Look for signs of atypia or malignancy.
+
*Look for signs of '''atypia or malignancy'''.
 
<gallery mode=packed heights=200>
 
<gallery mode=packed heights=200>
 
File:Histopathology of non-complex endometrial polyp without atypia.jpg|'''Non-complex endometrial polyp without atypia''', with a thick-walled blood vessel in middle - typical of endometrial polyps. Glands are regular.
 
File:Histopathology of non-complex endometrial polyp without atypia.jpg|'''Non-complex endometrial polyp without atypia''', with a thick-walled blood vessel in middle - typical of endometrial polyps. Glands are regular.

Revision as of 20:02, 30 September 2020

Author: Mikael Häggström [note 1]

Fixation

Generally 10% neutral buffered formalin.

  See also: General notes on fixation


Microscopic evaluation

Histopathologic and cytopathologic images.
(A) proliferative endometrium (Left: HE × 400) and proliferative endometrial cells (Right: HE × 100)
(B) secretory endometrium (Left: HE × 10) and secretory endometrial cells (Right: HE × 10)
(C) atrophic endometrium (Left: HE × 10) and atrophic endometrial cells (Right: HE × 10)
(D) mixed endometrium (Left: HE × 10) and mixed endometrial cells (Right: HE × 10)
(E): endometrial atypical hyperplasia (Left: HE × 10) and endometrial atypical cells (Right: HE × 200)
(F) endometrial carcinoma (Left: HE × 400) and endometrial cancer cells (Right: HE × 400).

The main objectives are:

  • Making a diagnosis of endometrioid polyp. An endometrial polyp may be diagnosed in the presence of 2 of the following 3:
  • Thick-walled vessels
  • Collagenous stroma
  • Epithelium on at least 3 sides
  • Look for signs of atypia or malignancy.

Reporting

Most importantly:

  • Presence or absence of atypia.

Optionally, report the type of epithelium at both the surface and gland coverings.

  See also: General notes on reporting


Notes

  1. For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.

Main page

References

  1. Rao, Shalinee; Sundaram, Sandhya; Narasimhan, Raghavan (2009). "Biological behavior of preneoplastic conditions of the endometrium: A retrospective 16-year study in south India ". Indian Journal of Medical and Paediatric Oncology 30 (4): 131. doi:10.4103/0971-5851.65335. ISSN 0971-5851. 
    - Figure- available via license: Creative Commons Attribution 2.0 Generic
  2. Rao, Shalinee; Sundaram, Sandhya; Narasimhan, Raghavan (2009). "Biological behavior of preneoplastic conditions of the endometrium: A retrospective 16-year study in south India ". Indian Journal of Medical and Paediatric Oncology 30 (4): 131. doi:10.4103/0971-5851.65335. ISSN 0971-5851. 
    - Figure- available via license: Creative Commons Attribution 2.0 Generic
  3. Mohamed Mokhtar Desouki. Uterus - Stromal tumors - Leiomyoma. pathology Outlines. Topic Completed: 1 August 2011. Revised: 15 December 2019

Image sources