Difference between revisions of "Endometrial polyp"
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{{Fixation - general notes}} | {{Fixation - general notes}} | ||
==Microscopic evaluation== | ==Microscopic evaluation== | ||
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The main objectives are: | The main objectives are: | ||
*Making a '''diagnosis''' of endometrioid polyp. An endometrial polyp may be diagnosed in the presence of 2 of the following 3: | *Making a '''diagnosis''' of endometrioid polyp. An endometrial polyp may be diagnosed in the presence of 2 of the following 3: |
Revision as of 15:37, 20 October 2020
Author:
Mikael Häggström [note 1]
Contents
Fixation
Generally 10% neutral buffered formalin.
See also: General notes on fixation
Microscopic evaluation
The main objectives are:
- Making a diagnosis of endometrioid polyp. An endometrial polyp may be diagnosed in the presence of 2 of the following 3:
- Thick-walled vessels
- Collagenous stroma
- Epithelium on at least 3 sides
- Look for signs of atypia or malignancy.
Complex hyperplasia without atypia: Cystically dilated endometrial glands lined by a single layer of columnar epithelium.[1]
Complex hyperplasia with atypia: Closely packed endometrial glands with sparse intervening stroma and stratification of the lining epithelium. Epithelial cells show cytological atypia with high nucleocytoplasmic ratio, irregular clumping of nuclear chromatin, and mitotic figures.[2]
Subserosal pedunculated uterine leiomyomas may present as endometrial polyps. They typically show smooth muscle in a whorled (fascicular) pattern[3] Further information: Smooth muscle tumor
Reporting
Most importantly:
- Presence or absence of atypia.
Optionally, report the type of epithelium at both the surface and gland coverings.
See also: General notes on reporting
Notes
- ↑ For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.
Main page
References
- ↑ Rao, Shalinee; Sundaram, Sandhya; Narasimhan, Raghavan (2009). "Biological behavior of preneoplastic conditions of the endometrium: A retrospective 16-year study in south India
". Indian Journal of Medical and Paediatric Oncology 30 (4): 131. doi: . ISSN 0971-5851.
- Figure- available via license: Creative Commons Attribution 2.0 Generic - ↑ Rao, Shalinee; Sundaram, Sandhya; Narasimhan, Raghavan (2009). "Biological behavior of preneoplastic conditions of the endometrium: A retrospective 16-year study in south India
". Indian Journal of Medical and Paediatric Oncology 30 (4): 131. doi: . ISSN 0971-5851.
- Figure- available via license: Creative Commons Attribution 2.0 Generic - ↑ Mohamed Mokhtar Desouki. Uterus - Stromal tumors - Leiomyoma. pathology Outlines. Topic Completed: 1 August 2011. Revised: 15 December 2019
Image sources