Difference between revisions of "Endoscopic gastrointestinal biopsies"

From patholines.org
Jump to navigation Jump to search
(Started)
 
(+Reports)
Line 4: Line 4:
 
}}
 
}}
 
{{Endoscopic biopsies}}
 
{{Endoscopic biopsies}}
 +
{{Comprehensiveness}}
 
{{Fixation - standard}}
 
{{Fixation - standard}}
 
==Gross processing==
 
==Gross processing==
Line 9: Line 10:
 
*Preferably stain with eosin if any fragment is smaller than about 0.3 cm
 
*Preferably stain with eosin if any fragment is smaller than about 0.3 cm
 
*Biopsies that are thicker than about 3-4 mm generally need to be bisected.
 
*Biopsies that are thicker than about 3-4 mm generally need to be bisected.
 +
 +
==Microscopic examination===
 +
===Example normal reports===
 +
;[[Esophagus]]:
 +
{|class=wikitable
 +
| {{Moderate-begin}}Middle third esophagus, biopsy:{{Moderate-end}}<br>Squamous mucosa without significant histopathologic changes.<br>{{Moderate-begin}}Negative for [[eosinophilic esophagitis]].{{Moderate-end}}
 +
|}
 +
 +
;[[Gastroesophageal junction]]:
 +
{|class=wikitable
 +
| {{Moderate-begin}}GE junction, biopsy:{{Moderate-end}}<br>Squamous mucosa, '''negative''' for significant histopathologic changes.<br>{{Moderate-begin}}Negative for gastric mucosa or intestinalized (Barrett's) mucosa.{{Moderate-end}}
 +
|}
 +
 +
;[[Stomach]]:
 +
{|class=wikitable
 +
| {{Moderate-begin}}Gastric, biopsy:{{Moderate-end}} Gastric mucosa without significant pathologic changes.<br>{{Comprehensive-begin}}Negative for helicobacter pylori organisms on H&E slide.{{Comprehensive-end}}
 +
|}
 +
 +
;[[Duodenum]]:
 +
{|class=wikitable
 +
| (Small bowel, biopsy:) Duodenal mucosa without significant histopathologic changes. (Negative for celiac disease.)
 +
|}
 +
 +
;[[Colon]]:
 +
{|class=wikitable
 +
| Colonic mucosa, negative for significant histopathologic changes.
 +
|}
 +
 
{{Bottom}}
 
{{Bottom}}

Revision as of 12:42, 28 November 2020

Author: Mikael Häggström [note 1]

Endoscopic biopsies   edit
Mostly:

Comprehensiveness

On this resource, the following formatting is used for comprehensiveness:

  • Minimal depth
  • (Moderate depth)
  • ((Comprehensive))

Fixation

Generally 10% neutral buffered formalin.

Gross processing

  • Count the number of fragments. They can be classified as “multiple” at over 5 or 6 specimens. Possibly add “Mixed with luminal material”.
  • Preferably stain with eosin if any fragment is smaller than about 0.3 cm
  • Biopsies that are thicker than about 3-4 mm generally need to be bisected.

Microscopic examination=

Example normal reports

Esophagus
(Middle third esophagus, biopsy:)
Squamous mucosa without significant histopathologic changes.
(Negative for eosinophilic esophagitis.)
Gastroesophageal junction
(GE junction, biopsy:)
Squamous mucosa, negative for significant histopathologic changes.
(Negative for gastric mucosa or intestinalized (Barrett's) mucosa.)
Stomach
(Gastric, biopsy:) Gastric mucosa without significant pathologic changes.
((Negative for helicobacter pylori organisms on H&E slide.))
Duodenum
(Small bowel, biopsy:) Duodenal mucosa without significant histopathologic changes. (Negative for celiac disease.)
Colon
Colonic mucosa, negative for significant histopathologic changes.

Notes

  1. For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.

Main page

References


Image sources