Endoscopic gastrointestinal biopsies
Author:
Mikael Häggström [note 1]
| Mostly: |
Contents
Comprehensiveness
On this resource, the following formatting is used for comprehensiveness:
- Minimal depth
- (Moderate depth)
- ((Comprehensive))
Fixation
Generally 10% neutral buffered formalin.
Gross processing
- Count the number of fragments. They can be classified as “multiple” at over 5 or 6 specimens. Possibly add “Mixed with luminal material”.
- Preferably stain with eosin if any fragment is smaller than about 0.3 cm
- Biopsies that are thicker than about 3-4 mm generally need to be bisected.
Microscopic examination=
Example normal reports
| (Middle third esophagus, biopsy:) Squamous mucosa without significant histopathologic changes. (Negative for eosinophilic esophagitis.) |
| (GE junction, biopsy:) Squamous mucosa, negative for significant histopathologic changes. (Negative for gastric mucosa or intestinalized (Barrett's) mucosa.) |
| (Gastric, biopsy:) Gastric mucosa without significant pathologic changes. ((Negative for helicobacter pylori organisms on H&E slide.)) |
| (Small bowel, biopsy:) Duodenal mucosa without significant histopathologic changes. (Negative for celiac disease.) |
| Colonic mucosa, negative for significant histopathologic changes. |
Notes
- ↑ For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.
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References
Image sources
