Difference between revisions of "Esophagus"
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Latest revision as of 19:23, 2 December 2022
Author:
Mikael Häggström [note 1]
| Mostly: |
Most common requests:
Subregions:
- Gastroesophageal junction, preferably also evaluate as such for lower esophagus, or where esophagus level is not specified.
This article deals with esophageal biopsies. For resections, see: Esophagus resection
Contents
Comprehensiveness
On this resource, the following formatting is used for comprehensiveness:
- Minimal depth
- (Moderate depth)
- ((Comprehensive))
Microscopic evaluation
On esophageal biopsies, look at least for esophagitis:
Esophagitis
Look for signs of (reflux) esophagitis, mainly:[1]
- Inflammatory cells, especially when intra-epithelial. Neutrophils confer a diagnosis of acute inflammation, while plasma cells, eosinophils and excess T cells confer a diagnosis of chronic inflammation. In eosinophil-predominant inflammation, also evaluate as suspected eosinophilic esophagitis.
- Basal cell hyperplasia exceeding 15 - 20% of the epithelial thickness.
- Stromal papillae reaching upper third of the epithelium.
- Loss of orientation of superficial epithelial cells.
- Ballooned squamous cells
An intra-epithelial eosinophil (characterized by its bilobed nucleus despite scant visible eosinophilic cytoplasm)
Microscopy report
Example normal report for an esophagus biopsy:
| (Middle third esophagus, biopsy:) Squamous mucosa without significant histopathologic changes. ((Negative for eosinophilic esophagitis.)) |
Example report with signs of reflux:
| (Mid esophagus, biopsy:) Squamous mucosa with reactive changes consistent with reflux. ((Negative for eosinophilic esophagitis.)) |
Notes
- ↑ For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.
Main page
References
- ↑ Elliot Weisenberg. Esophagus - Esophagitis - Reflux esophagitis / gastroesophageal reflux disease. Pathology Outlines. Topic Completed: 1 October 2012. Minor changes: 8 July 2020
Image sources
