Difference between revisions of "Fibrocystic breast changes"

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|author1=[[User:Mikael Häggström|Mikael Häggström]]
 
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==Presentations==
 
==Presentations==
 
*[[Breast biopsy or excision]]
 
*[[Breast biopsy or excision]]
 
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==Microscopic examination==
 
==Microscopic examination==
 
Types:
 
Types:

Revision as of 00:00, 19 June 2022

Author: Mikael Häggström [note 1]

Presentations

Microscopic examination

Types:

Differential diagnosis

Sclerosing adenosis may look similar to invasive ductal carcinoma (IDC), but IDC will:[1]

  • Not be lobular at low power
  • Have marked cellular atypia
  • Have no myoepithelial cells surrounding ducts.

When unsure, perform immunohistochemistry for myoepithelial markers (preferably p63 and calponin in breast lesions):

Immunostain with a myoepithelial marker (calponin) in sclerosing adenosis, showing myoepithelial cells surrounding the ducts, thereby excluding invasive carcinoma.

Notes

  1. For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.

Main page

References

  1. 1.0 1.1 Jaya Ruth Asirvatham, M.B.B.S., Julie M. Jorns, M.D.. Breast - Fibrocystic changes - Sclerosing adenosis. Pathology Outlines. Topic Completed: 1 January 2015. Minor changes: 31 December 2020

Image sources