Gastroesophageal junction

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Author: Mikael Häggström [note 1]

Intestinalized mucosa: Low-power view shows a predominantly columnar-lined surface epithelium, pits of gastric type, and underlying mucous glands with occasional intestinalized crypts.

The main finding to look for is intestinalized mucosa (Barret's esophagus), which is defined as the presence of columnar epithelium with goblet cells.[1] A true goblet cell should have rounded shape, clear to bluish cytoplasmic mucin, and be randomly scattered.[2] The mucin usually indents the nucleus.[2]

Report

Examples:

Gastroesophageal junctional mucosa with chronic inflammation and reactive changes, non-specific.
Negative for intestinalized (Barrett's) mucosa.
Squamous mucosa, negative for significant histopathologic changes.
Negative for gastric mucosa or intestinalized (Barrett's) mucosa.

Notes

  1. For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.

Main page

References

  1. . Barrett Esophagus. Stanford University School of Medicine. Retrieved on 2020-09-01.
  2. 2.0 2.1 Dipti M. Karamchandani. Esophagus - Premalignant - Barrett esophagus. Topic Completed: 19 March 2020, Minor changes: 29 June 2020

Image sources