Difference between revisions of "Heart"
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− | *[[Autopsy of myocardial infarction]] | + | {{Top |
+ | |author1=[[User:Mikael Häggström|Mikael Häggström]] | ||
+ | |author2= | ||
+ | }} | ||
+ | |||
+ | {{Fixation - standard}} | ||
+ | {{Fixation - general notes}} | ||
+ | |||
+ | ==Presentations== | ||
+ | *[[Heart autopsy]] | ||
+ | :*[[Autopsy of myocardial infarction]] | ||
+ | |||
+ | ==Basic microscopic screening== | ||
+ | Generally check for signs of myocardial infarction. | ||
+ | {{Further|Autopsy of myocardial infarction}} | ||
+ | |||
+ | ===Common findings=== | ||
+ | <gallery mode=packed heights=150> | ||
+ | File:Myocardial lipofuscin (annotated).jpg|Myocardial '''lipofuscin''' reflects normal ageing rather than any cardiac pathology,<ref name="KakimotoOkada2019">{{cite journal|last1=Kakimoto|first1=Yu|last2=Okada|first2=Chisa|last3=Kawabe|first3=Noboru|last4=Sasaki|first4=Ayumi|last5=Tsukamoto|first5=Hideo|last6=Nagao|first6=Ryoko|last7=Osawa|first7=Motoki|title=Myocardial lipofuscin accumulation in ageing and sudden cardiac death|journal=Scientific Reports|volume=9|issue=1|year=2019|issn=2045-2322|doi=10.1038/s41598-019-40250-0}}</ref> and does not need mentioning in the elderly. | ||
+ | File:Histopathology of ruptured intercalated discs.jpg|Ruptured intercalated discs. {{Further|Ruptured intercalated discs|linebreak=no}} | ||
+ | File:Histopathology of dense fibrous scar replacing myocyte loss in myocardial infarction.jpg|'''Fibrosis'''. {{further|Myocardial fibrosis|linebreak=no}} | ||
+ | File:Histopathology of myocardial hypertrophy.jpg|Myocardial '''hypertrophy''' (in right image, compared to normal at left). | ||
+ | File:Histopathology of moderate myocardial hypertrophy.jpg|Rectangular "'''Boxcar'''" nuclei: Look for myocardial hypertrophy, especially when enlarged. Otherwise, [[ruptured intercalated discs]] can cause square shaped nuclei. | ||
+ | File:Histopathology of lymphocytic myocarditis with myocyte necrosis, annotated.jpg|'''Lymphocytic myocarditis''' (white arrow points to a lymphocyte), commonly showing myocyte necrosis (black arrow), seen as hypereosinophilic cytoplasm with loss of striations. | ||
+ | </gallery> | ||
+ | {{Bottom}} |
Revision as of 12:57, 14 April 2021
Author:
Mikael Häggström [note 1]
Contents
Fixation
Generally 10% neutral buffered formalin.
See also: General notes on fixation
Presentations
Basic microscopic screening
Generally check for signs of myocardial infarction. Further information: Autopsy of myocardial infarction
Common findings
Myocardial lipofuscin reflects normal ageing rather than any cardiac pathology,[1] and does not need mentioning in the elderly.
Ruptured intercalated discs. Further information: Ruptured intercalated discs
Fibrosis. Further information: Myocardial fibrosis
Rectangular "Boxcar" nuclei: Look for myocardial hypertrophy, especially when enlarged. Otherwise, ruptured intercalated discs can cause square shaped nuclei.
Notes
- ↑ For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.
Main page
References
Image sources