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==Fixation==
 
 
{{Fixation - standard}}
 
{{Fixation - standard}}
 
{{Fixation - general notes}}
 
{{Fixation - general notes}}
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{{Further|Autopsy of myocardial infarction}}
 
{{Further|Autopsy of myocardial infarction}}
  
==Common findings==
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===Common findings===
<gallery>
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<gallery mode=packed heights=150>
File:Myocardial lipofuscin (annotated).jpg|Myocardial lipofuscin reflects normal ageing rather than any cardiac pathology.<ref name="KakimotoOkada2019">{{cite journal|last1=Kakimoto|first1=Yu|last2=Okada|first2=Chisa|last3=Kawabe|first3=Noboru|last4=Sasaki|first4=Ayumi|last5=Tsukamoto|first5=Hideo|last6=Nagao|first6=Ryoko|last7=Osawa|first7=Motoki|title=Myocardial lipofuscin accumulation in ageing and sudden cardiac death|journal=Scientific Reports|volume=9|issue=1|year=2019|issn=2045-2322|doi=10.1038/s41598-019-40250-0}}</ref>
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File:Myocardial lipofuscin (annotated).jpg|Myocardial '''lipofuscin''' reflects normal ageing rather than any cardiac pathology,<ref name="KakimotoOkada2019">{{cite journal|last1=Kakimoto|first1=Yu|last2=Okada|first2=Chisa|last3=Kawabe|first3=Noboru|last4=Sasaki|first4=Ayumi|last5=Tsukamoto|first5=Hideo|last6=Nagao|first6=Ryoko|last7=Osawa|first7=Motoki|title=Myocardial lipofuscin accumulation in ageing and sudden cardiac death|journal=Scientific Reports|volume=9|issue=1|year=2019|issn=2045-2322|doi=10.1038/s41598-019-40250-0}}</ref> and does not need mentioning in the elderly.
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File:Histopathology of ruptured intercalated discs.jpg|Ruptured intercalated discs. {{Further|Ruptured intercalated discs|linebreak=no}}
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File:Histopathology of dense fibrous scar replacing myocyte loss in myocardial infarction.jpg|'''Fibrosis'''. {{further|Myocardial fibrosis|linebreak=no}}
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File:Histopathology of myocardial hypertrophy.jpg|Myocardial '''hypertrophy''' (in right image, compared to normal at left).
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File:Histopathology of moderate myocardial hypertrophy.jpg|Rectangular "'''Boxcar'''" nuclei: Look for myocardial hypertrophy, especially when enlarged. Otherwise, [[ruptured intercalated discs]] can cause square shaped nuclei.
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File:Histopathology of lymphocytic myocarditis with myocyte necrosis, annotated.jpg|'''Lymphocytic myocarditis''' (white arrow points to a lymphocyte), commonly showing myocyte necrosis (black arrow), seen as hypereosinophilic cytoplasm with loss of striations.
 
</gallery>
 
</gallery>
 
 
{{Bottom}}
 
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Revision as of 12:57, 14 April 2021

Author: Mikael Häggström [note 1]

Fixation

Generally 10% neutral buffered formalin.

  See also: General notes on fixation


Presentations

Basic microscopic screening

Generally check for signs of myocardial infarction. Further information: Autopsy of myocardial infarction

Common findings

Notes

  1. For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.

Main page

References

  1. Kakimoto, Yu; Okada, Chisa; Kawabe, Noboru; Sasaki, Ayumi; Tsukamoto, Hideo; Nagao, Ryoko; Osawa, Motoki (2019). "Myocardial lipofuscin accumulation in ageing and sudden cardiac death ". Scientific Reports 9 (1). doi:10.1038/s41598-019-40250-0. ISSN 2045-2322. 

Image sources