Hypertrophic scar

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Author: Mikael Häggström [note 1]

Contents

Gross processing

Gross pathology processing of skin lesions with benign appearance, by lesion size:[1]
<4 mm 4 - 8 mm 9 - 15 mm

 

 

 

In table above, each top image shows recommended lines for cutting out slices to be submitted for further processing. Bottom image shows which side of the slice that should be put to microtomy. Dashed lines here mean that either side could be used. Further information: Gross processing of skin excisions

Microscopic evaluation

 
A hypertrophic scar is characterized by replacement of the papillary and reticular dermis by scar tissue with prominent vertically oriented blood vessels.[2]
Keloid versus hypertrophic scar - Typical findings
Keloid Hypertrophic scar
   
Flattening of the overlying epidermis No Yes
Scarring of the papillary dermis No Yes
Collagen Thick hyalinized bundles Whorl-like or nodular arrangements
Vertically oriented blood vessels Yes No
Prominent disarray of fibrous fascicles/nodules Yes No
Tongue-like advancing edge underneath normal-appearing epidermis and papillary dermis Yes No
Horizontal cellular fibrous band in the upper reticular dermis Yes No
Prominent fascia-like fibrous band Yes No

Notes

  1. For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.

Main page

References

  1. ". Ochsner J 5 (2): 22–33. 2003. PMID 22826680. PMC: 3399331. Archived from the original. . 
    - With a "standard histologic examination" that, in addition to the lesion, only includes one section from each side along the longest diameter of the specimen.
    - It also shows an example of circular coverage, with equal coverage distance in all four directions.
    - The entire specimen may be submitted if the risk of malignancy is high.
  2. Rabello, FB; Souza, CD; Farina Jr, JA (2014). "Update on hypertrophic scar treatment ". Clinics 69 (8): 565–573. doi:10.6061/clinics/2014(08)11. ISSN 18075932. 

Image sources