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On microscopy from a [[brain autopsy]], routinely look for '''lacunar infarcts''', especially in basal ganglia, as they are most common in the deep nuclei of the brain.<ref>{{Cite book|title=Neuropsychology : a review of science and practice, volume III|others=Koffler, Sandra,, Mahone, E. (E. Mark),, Marcopulos, Bernice A.,, Johnson-Greene, Douglas Eric, 1962-, Smith, Glenn E.|isbn=978-0-19-065256-2|location=New York, NY|oclc=1078637067|date = 2018-12-17}}</ref>
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File:Histopathology of lacunar infarct with siderophages.jpg|A small lacunar infarct of the basal ganglia. It characteristically shows a gap surrounded by disrupted (almost chicken wire-like) neuropil. Sometimes they contain some inflammatory cells including siderophages (brown-golden cell in middle).
File:Histopathology of a lacunar cerebral infarct.jpg|A lacunar infarct in the thalamus.
File:Histopathology of multiple lacunar infarcts and arteriosclerosis in basal ganglia.jpg|thumb|Multiple lacunar infarcts, explained by arteriosclerosis (a severely narrowed and calcified artery seen) in basal ganglia. Lacunar infarcts may look diffusely distributed but are generally less sharply demarcated than tearing '''[[artifact]]s'''.
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