Difference between revisions of "Lichen sclerosus"
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(→Reporting: Even absence) |
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*Sclerosis of the dermis | *Sclerosis of the dermis | ||
*Lymphocytes in the dermis | *Lymphocytes in the dermis | ||
| − | Also look for dysplasia | + | Also look for dysplasia,<ref name="Shelley2006">{{Cite journal | last1 = Shelley | first1 = W. B. | last2 = Shelley | first2 = E. D. | last3 = Amurao | first3 = C. V. | doi = 10.1111/j.1365-4632.2006.02978.x | title = Treatment of lichen sclerosus with antibiotics | journal = International Journal of Dermatology | volume = 45 | issue = 9 | pages = 1104–1106 | year = 2006 | pmid = 16961523| pmc = }}</ref> especially in the basal layer, which, depending on location, would confer a diagnosis of [[actinic keratosis]] or [[vulvar intraepithelial neoplasia]]. |
==Reporting== | ==Reporting== | ||
Latest revision as of 18:10, 22 September 2021
Author:
Mikael Häggström [note 1]
Contents
Presentations
Mainly including:
Fixation
Generally 10% neutral buffered formalin.
See also: General notes on fixation
Gross processing
See also: General notes on gross processing
Microscopic evaluation
Micrograph of extragenital lichen sclerosus: epidermal atrophy, follicular plugging and basal vacuolization, and sclerosis with initial homogenization of collagen in the dermis.[1]
Findings associated with lichen sclerosus are:[2]
- Hyperkeratosis
- Atrophic epidermis
- Sclerosis of the dermis
- Lymphocytes in the dermis
Also look for dysplasia,[3] especially in the basal layer, which, depending on location, would confer a diagnosis of actinic keratosis or vulvar intraepithelial neoplasia.
Reporting
Report:
- Presence or absence of lichen sclerosus
- Optionally, even the absence of dysplasia.
See also: General notes on reporting
Notes
- ↑ For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.
Main page
References
- ↑ Jędrowiak, Anna; Kobusiewicz, Aleksandra; Trznadel-Grodzka, Ewa; Kaszuba, Andrzej (2018). "Dermoscopic findings in extragenital lichen sclerosus
". Our Dermatology Online 9 (2): 197–199. doi:. ISSN 20819390.
- "Figures - available via license: CC BY 4.0" - ↑ Lisa K Pappas-Taffer. Lichen Sclerosus. EMedicine. Updated: May 17, 2018
- ↑ Shelley, W. B.; Shelley, E. D.; Amurao, C. V. (2006). "Treatment of lichen sclerosus with antibiotics ". International Journal of Dermatology 45 (9): 1104–1106. doi:. PMID 16961523.
Image sources
