Lung tumor
Author:
Mikael Häggström [note 1]
Contents
Comprehensiveness
On this resource, the following formatting is used for comprehensiveness:
- Minimal depth
- (Moderate depth)
- ((Comprehensive))
Presentations
- Bronchial lavage
- Lung needle biopsy
- Lung wedge resection or lobectomy
- Lung autopsy
Gross processing
In tumor resection:[1]
- Measure the specimen in 3 dimensions.
- Describe any included pleural surface, including color, and any presence of granularity, adhesions, retraction, or tumor.
- Serially section the specimen. Describe the cut surface, including color and consistency, and any focal lesions.
- Measure tumor size as a maximum diameter (or 3 dimensions)
- Determine location: Which lobe if applicable, and if it is peripheral, central or hilar.
- Margin length to pleura and hilum/surgical margin.
- Any involvement of major bronchi or blood vessels.
- Any abnormal lymph nodes, including hilar ones if available.
Photograph all tumors.
Squamous cell carcinoma involving a subsegmental bronchus with distal chronic obstructive pneumonia. The tumor is seen as a rounded nodule, approximately 2 cm in diameter, proximal to a more irregular focus of chronic obstructive pneumonia with fibrosis.
Microscopic evaluation
Medical imaging provides a major clue as to whether a lung tumor is benign or malignant, where lesions smaller than 2 cm are likely to be benign, whereas lesions larger than 2 cm are malignant (that is, lung cancer) in 85% of cases.[2]
Subsequently distribution of benign tumors and lung cancers, respectively, are as follows:[2]
Benign lung tumors:
- Hamartomas - 76%
- Benign fibrous mesothelioma/solitary fibrous tumor (SFT) - 12.3%
- Inflammatory pseudotumor (IPT) - 5.4%
- Lipoma - 1.5%
- Leiomyoma - 1.5%
- Other - 3.3%
Gallery of lung cancers
Lung adenocarcinoma, with lepidic pattern shown, wherein tumors cells cover alveolar walls.
Large cell carcinoma of the lung: neoplastic cells with abundant pale eosinophilic cytoplasm
Squamous-cell carcinoma of the lung. Typical squamous-cell carcinoma cells are large with abundant eosinophilic cytoplasm and large, often vesicular, nuclei.[3]
Notes
- ↑ For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.
Main page
References
- ↑ . Pulmonary pathology grossing guidelines. Retrieved on 2021-03-17.
- ↑ 2.0 2.1 Alain C. Borczuk (2008). "Benign Tumors and Tumorlike Conditions of the Lung ". Archives of Pathology & Laboratory Medicine 132 (7). Archived from the original. .
- ↑ Dr Nicholas Turnbull, A/Prof Patrick Emanual (2014-05-03). Squamous cell carcinoma pathology. DermNetz.
Image sources
