Difference between revisions of "Lungs"
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==Tissue sampling== | ==Tissue sampling== | ||
*[[Lung autopsy]] | *[[Lung autopsy]] | ||
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*[[Lung wedge resection and lobectomy]] | *[[Lung wedge resection and lobectomy]] | ||
*[[Lung biopsy]] | *[[Lung biopsy]] | ||
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==Basic microscopic screening== | ==Basic microscopic screening== | ||
:''For screening of lung autopsies, see '''[[Lung autopsy]]''' '' | :''For screening of lung autopsies, see '''[[Lung autopsy]]''' '' | ||
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File:Histopathology of respiratory epithelial shedding.jpg|Respiratory '''epithelial shedding''' in a small bronchus. If present, look for vascular leakage, mucus hypersecretion and/or widespread airway narrowing, together indicating asthma.<ref>{{cite book | last=Madea | first=B | title=Handbook of forensic medicine | publisher=Wiley-Blackwell | publication-place=Hoboken, N.J | year=2014 | isbn=978-1-118-57062-3 | oclc=872114659 | ref=harv}}</ref> | File:Histopathology of respiratory epithelial shedding.jpg|Respiratory '''epithelial shedding''' in a small bronchus. If present, look for vascular leakage, mucus hypersecretion and/or widespread airway narrowing, together indicating asthma.<ref>{{cite book | last=Madea | first=B | title=Handbook of forensic medicine | publisher=Wiley-Blackwell | publication-place=Hoboken, N.J | year=2014 | isbn=978-1-118-57062-3 | oclc=872114659 | ref=harv}}</ref> | ||
</gallery> | </gallery> | ||
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+ | ===Other pertinent findings=== | ||
+ | <gallery mode=packed heights=220> | ||
+ | File:Histopathology of diffuse alveolar damage.jpg|'''hyaline membranes''', suggesting '''diffuse alveolar damage'''. | ||
+ | File:Histopathology of pulmonary aspergillosis.jpg|Pulmonary '''aspergillosis''', seen as acutely branching septated hyphae.<ref>{{cite web|url=https://wellcomecollection.org/works/rsfbcjkv%7Ctitle=Lung: invasive pulmonary aspergillosis with AIDS|website=Wellcome Collection|accessdate=2024-02-21}} License: CC0 1.0 Universal</ref> | ||
+ | File:Histopathology of pulmonary mucormycosis.jpg|Pulmonary '''mucormycosis''', seen as non-septated and broad-branching, and sometimes branching at right angles (black arrow).<ref name="pmid27423701">{{cite journal| author=Lee JH, Hyun JS, Kang DY, Lee HJ, Park SG| title=Rare complication of bronchoesophageal fistula due to pulmonary mucormycosis after induction chemotherapy for acute myeloid leukemia: a case report. | journal=J Med Case Rep | year= 2016 | volume= 10 | issue= | pages= 195 | pmid=27423701 | doi=10.1186/s13256-016-0991-7 | pmc=4947348 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27423701 }}<br>- "This article is distributed under the terms of the Creative Commons Attribution 4.0 International License"</ref> | ||
+ | </gallery> | ||
+ | For fungi not conforming to the two main forms above, a general pathologist may attempt to get input by readily available expertise locally, but if it cannot be readily speciated, then it's generally acceptable to simply report as fungi present. | ||
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Latest revision as of 17:28, 21 February 2024
Author:
Mikael Häggström [note 1]
Contents
Tissue sampling
Fixation
Generally 10% neutral buffered formalin.
Presentations
Basic microscopic screening
- For screening of lung autopsies, see Lung autopsy
Mainly look for carcinoma. Further information: Lung tumor
If granulomas are seen, generally stain for acid-fast bacteria and fungi.
Common findings
Active searching for them is not mandatory.
Anthracosis (interstitial black material).
Respiratory epithelial shedding in a small bronchus. If present, look for vascular leakage, mucus hypersecretion and/or widespread airway narrowing, together indicating asthma.[1]
Other pertinent findings
Pulmonary aspergillosis, seen as acutely branching septated hyphae.[2]
Pulmonary mucormycosis, seen as non-septated and broad-branching, and sometimes branching at right angles (black arrow).[3]
For fungi not conforming to the two main forms above, a general pathologist may attempt to get input by readily available expertise locally, but if it cannot be readily speciated, then it's generally acceptable to simply report as fungi present.
Notes
- ↑ For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.
Main page
References
- ↑ Madea, B (2014). Handbook of forensic medicine . Hoboken, N.J: Wiley-Blackwell. ISBN 978-1-118-57062-3. OCLC 872114659.
- ↑ Error on call to Template:cite web: Parameters url and title must be specified. . Wellcome Collection. Retrieved on 2024-02-21. License: CC0 1.0 Universal
- ↑ Lee JH, Hyun JS, Kang DY, Lee HJ, Park SG (2016). "Rare complication of bronchoesophageal fistula due to pulmonary mucormycosis after induction chemotherapy for acute myeloid leukemia: a case report.
". J Med Case Rep 10: 195. doi: . PMID 27423701. PMC: 4947348. Archived from the original. .
- "This article is distributed under the terms of the Creative Commons Attribution 4.0 International License"
Image sources