Lymph nodes

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Revision as of 18:48, 13 August 2020 by Mikael Häggström (talk | contribs) (Cleanup)
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Author: Mikael Häggström [note 1]

Lymph node metastasis from a neuroendocrine tumor of the midgut.

Gross processing

In samples with tumors, slice through all included fat while palpating and looking for lymph nodes, and submit all that are found.

Microscopic examination

Look for whatever pathology is indicated by the referral, or findings in other submitted specimens. The main target conditions are:

  • Metastasis, which usually looks similar to the primary tumor (neuroendocrine tumor in picture at right).
  • Reactive lymphadenopathy, by inflammation in an adjacent area, or systemic.

Reactive lymphadenopathy

Follicular hyperplasia is the most common pattern of reactive lymphadenopathy.[1] It is usually associated with varying degrees of paracortical and/or sinus hyperplasia.

It usually has varying amount of paracortical and/or sinus hyperplasia.[1] Older age, increased follicular density (especially back-to-back arrangement) and areas of diffuse nodal effacement leads to a suspicion of follicular lymphoma.[1] Further information: Follicular lymphoma versus reactive follicular hyperplasia

Notes

  1. For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.

Main page

References

  1. 1.0 1.1 1.2 Weiss, Lawrence M; O'Malley, Dennis (2013). "Benign lymphadenopathies ". Modern Pathology 26 (S1): S88–S96. doi:10.1038/modpathol.2012.176. ISSN 0893-3952. 

Image sources