Difference between revisions of "Myocardial fibrosis"
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File:Subepicardial fibrosis.jpg|'''Subepicardial fibrosis''' (epicardium at top). | File:Subepicardial fibrosis.jpg|'''Subepicardial fibrosis''' (epicardium at top). | ||
File:Histopathology of dense fibrous scar replacing myocyte loss in myocardial infarction.jpg|'''Replacement fibrosis''' in myocardial infarction, typically being boundless, dense and not conforming to the other types. | File:Histopathology of dense fibrous scar replacing myocyte loss in myocardial infarction.jpg|'''Replacement fibrosis''' in myocardial infarction, typically being boundless, dense and not conforming to the other types. | ||
+ | File:Histopathology of fat deposition in myocardial infarction scar.jpg|Fat deposition further indicates '''replacement fibrosis''' of a previous myocardial infarction.<ref name="ChenitiSridi2019">{{cite journal|last1=Cheniti|first1=Ghassen|last2=Sridi|first2=Soumaya|last3=Sacher|first3=Frederic|last4=Chaumeil|first4=Arnaud|last5=Pillois|first5=Xavier|last6=Takigawa|first6=Masateru|last7=Frontera|first7=Antonio|last8=Vlachos|first8=Konstantinos|last9=Martin|first9=Claire A.|last10=Teijeira|first10=Elvis|last11=Kitamura|first11=Takeshi|last12=Lam|first12=Anna|last13=Bourier|first13=Felix|last14=Puyo|first14=Stephane|last15=Duchateau|first15=Josselin|last16=Denis|first16=Arnaud|last17=Pambrun|first17=Thomas|last18=Chauvel|first18=Remi|last19=Derval|first19=Nicolas|last20=Laurent|first20=François|last21=Montaudon|first21=Michel|last22=Hocini|first22=Meleze|last23=Haissaguerre|first23=Michel|last24=Jais|first24=Pierre|last25=Cochet|first25=Hubert|title=Post–Myocardial Infarction Scar With Fat Deposition Shows Specific Electrophysiological Properties and Worse Outcome After Ventricular Tachycardia Ablation|journal=Journal of the American Heart Association|volume=8|issue=15|year=2019|issn=2047-9980|doi=10.1161/JAHA.119.012482}}</ref> | ||
</gallery> | </gallery> | ||
Revision as of 17:33, 21 May 2021
Author:
Mikael Häggström [note 1]
Contents
Presentations
Microscopic evaluation
In case of myocardial fibrosis, attempt to distinguish between the following:
- Interstitial fibrosis, which is unspecific,[1] (and may simply reported as such).[notes 1]
- Subepicardial fibrosis, also unspecific (and may simply be reported as such).[notes 2]
- Replacement fibrosis, which indicates an older infarction.[1]
Fat deposition further indicates replacement fibrosis of a previous myocardial infarction.[2]
Reporting
Example (if uncertain whether there is replacement fibrosis or merely subepicardial fibrosis):
Fibrosis of mainly replacement-type which may indicate an older infarction. |
Notes
- ↑ Interstitial fibrosis has been described in congestive heart failure, hypertension, and normal aging. (Chute, 2019)
- ↑ Subepicardial fibrosis is associated with non-infarction diagnoses such as myocarditis and non-ischemic cardiomyopathy.
- Gräni, Christoph; Eichhorn, Christian; Bière, Loïc; Kaneko, Kyoichi; Murthy, Venkatesh L.; Agarwal, Vikram; Aghayev, Ayaz; Steigner, Michael; et al. (2019). "Comparison of myocardial fibrosis quantification methods by cardiovascular magnetic resonance imaging for risk stratification of patients with suspected myocarditis ". Journal of Cardiovascular Magnetic Resonance 21 (1). doi: . ISSN 1532-429X.
- Bhaskaran, Ashwin; Tung, Roderick; Stevenson, William G.; Kumar, Saurabh (2019). "Catheter Ablation of VT in Non-Ischaemic Cardiomyopathies: Endocardial, Epicardial and Intramural Approaches ". Heart, Lung and Circulation 28 (1): 84–101. doi: . ISSN 14439506.
- ↑ For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.
Main page
References
- ↑ 1.0 1.1 Chute, Michael; Aujla, Preetinder; Jana, Sayantan; Kassiri, Zamaneh (2019). "The Non-Fibrillar Side of Fibrosis: Contribution of the Basement Membrane, Proteoglycans, and Glycoproteins to Myocardial Fibrosis ". Journal of Cardiovascular Development and Disease 6 (4): 35. doi: . ISSN 2308-3425.
- ↑ Cheniti, Ghassen; Sridi, Soumaya; Sacher, Frederic; Chaumeil, Arnaud; Pillois, Xavier; Takigawa, Masateru; Frontera, Antonio; Vlachos, Konstantinos; et al. (2019). "Post–Myocardial Infarction Scar With Fat Deposition Shows Specific Electrophysiological Properties and Worse Outcome After Ventricular Tachycardia Ablation ". Journal of the American Heart Association 8 (15). doi: . ISSN 2047-9980.
Image sources