Osteomyelitis
Revision as of 09:30, 25 November 2020 by Mikael Häggström (talk | contribs) (→Gross processing: Example)
Author:
Mikael Häggström [note 1]
Contents
Gross processing
- Measure the specimen
- Put in decalcification, after bisection of visibly affected areas if needed for penetration of the solution
- Take sections of visibly afected areas.
- Potentially sample as a standard amputation, such as for toe
Microscopic evaluation
The main sign of acute osteomyelitis is the presence of numerous neutrophils in the stroma. It may also have lymphocytes, plasma cells, bone necrosis,' capillary proliferation and fibrosis.[1]
Further workup
For toe amputations, determine its extent, particularly compared to the bony surgical or articular margin. Start at the margin and scan the bone at at least intermediate magnification until significant inflammation is seen. Preferably make a mark there and measure the distance from the mark to the margin.
Microscopic report
Example:
(A. Left third toe, amputation:) Toe with ulcer and osteomyelitis. Osteomyelitis involves the distal phalanx, middle phalanx and proximal phalanx. Osteomyelitis is 2.0 cm from the proximal articular surface of the proximal phalanx. |
Notes
- ↑ For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.
Main page
References
- ↑ Dariusz Borys. Bone & joints - Osteomyelitis - Bacterial osteomyelitis (acute). PathologyOutlines. Topic Completed: 1 June 2012. Minor changes: 28 June 2019
Image sources