Difference between revisions of "Ovarian tumor"
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!rowspan=3| [[Germ cell tumor]] !! Mature cystic [[teratoma]] | !rowspan=3| [[Germ cell tumor]] !! Mature cystic [[teratoma]] | ||
− | | 46,0% || 0 | + | | 46,0% || 0.17% to 2%<ref name="MandalBadhe2012">{{cite journal|last1=Mandal|first1=Shramana|last2=Badhe|first2=Bhawana A.|title=Malignant Transformation in a Mature Teratoma with Metastatic Deposits in the Omentum: A Case Report|journal=Case Reports in Pathology|volume=2012|year=2012|pages=1–3|issn=2090-6781|doi=10.1155/2012/568062}}</ref> || Cystic, with elements of all 3 [[germ layer]]s ([[endoderm]], [[mesoderm]] and [[ectoderm]]).<ref>{{cite web|url=https://www.pathologyoutlines.com/topic/skintumornonmelanocyticbenigncysticteratoma.html|title=Skin nonmelanocytic tumor - Other tumors of skin - Benign (mature) cystic teratoma|author=Hillary Rose Elwood|website=pathology Outlines}} Topic Completed: 1 November 2016. Revised: 4 April 2019</ref> || [[File:Mature Cystic Teratoma of the Ovary Hair Follicles (4047144010).jpg|thumb|190px|Hair follicles.]] |
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! [[Immature teratoma]] | ! [[Immature teratoma]] | ||
− | | 2,5% || 100 | + | | 2,5% || 100% || A [[teratoma]] that contains [[anaplastic]] immature elements, and is often synonymous with ''malignant teratoma''.<ref name="SunDing2019">{{cite journal|last1=Sun|first1=Hang|last2=Ding|first2=Hongxin|last3=Wang|first3=Jianjun|last4=Zhang|first4=Emma|last5=Fang|first5=Yihua|last6=Li|first6=Zhenhua|last7=Yu|first7=Xiao|last8=Wang|first8=Chongren|last9=Zhao|first9=Yifan|last10=Chen|first10=Kan|last11=Wen|first11=Siwan|last12=Li|first12=Liang|last13=Shan|first13=Shan|last14=Hong|first14=Liu|last15=Chen|first15=Face|last16=Su|first16=Pu|title=The differences between gonadal and extra-gonadal malignant teratomas in both genders and the effects of chemotherapy|journal=BMC Cancer|volume=19|issue=1|year=2019|issn=1471-2407|doi=10.1186/s12885-019-5598-0}}</ref> || [[File:Histopathology of immature teratoma of the ovary.jpg|200px]] |
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! Other germ cell tumors | ! Other germ cell tumors | ||
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!rowspan=4| [[Surface epithelial-stromal tumor]] !! Serous tumor | !rowspan=4| [[Surface epithelial-stromal tumor]] !! Serous tumor | ||
− | | 25,3% || 18 | + | | 25,3% || 18.5% || Benign serous tumors of the right ovarian cyst are thinwalled unilocular cysts that are lined by ciliated pseudostratified cuboidal or columnar epithelium.<ref name="BaradwanAlalyani2018">{{cite journal|last1=Baradwan|first1=Saeed|last2=Alalyani|first2=Haneen|last3=Baradwan|first3=Amira|last4=Baradwan|first4=Afnan|last5=Al-Ghamdi|first5=Maram|last6=Alnemari|first6=Jameel|last7=Al-Jaroudi|first7=Dania|title=Bilateral ovarian masses with different histopathology in each ovary|journal=Clinical Case Reports|volume=6|issue=5|year=2018|pages=784–787|issn=20500904|doi=10.1002/ccr3.1466}}</ref> || [[File:Histopathology of lining of a benign serous tumor of the ovary.jpg|200px]] |
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! Mucinous tumor | ! Mucinous tumor | ||
− | | 15,7% || 8 | + | | 15,7% || 8.8% || Benign mucinous tumors of the ovary consist of simple, nonstratified columnar epithelium with basally-located hyperchromatic nuclei and resemble gastric foveolar epithelium.<ref name="BaradwanAlalyani2018"/> || [[File:Histopathology of lining of a benign mucinous tumor of the ovary.jpg|200px]] |
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! [[Endometrioid tumor]] | ! [[Endometrioid tumor]] | ||
− | | 1,1% || 100 | + | | 1,1% || Almost 100% || Tubular glands, resembling endometrium.<ref>{{cite web|url=https://www.pathologyoutlines.com/topic/ovarytumorendometrioid.html|title=Ovary tumor - Endometrioid tumors - General|author=Shahrzad Ehdaivand|website=Pathology Outlines}} Topic Completed: 1 December 2012. Revised: 6 March 2020</ref> || [[File:Histopathology of well-differentiated endometrioid adenocarcinoma.png|200px]] |
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! Other surface-epithelial tumors | ! Other surface-epithelial tumors | ||
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!rowspan=3| [[Sex cord-stromal tumor]] !! [[Ovarian fibroma]] | !rowspan=3| [[Sex cord-stromal tumor]] !! [[Ovarian fibroma]] | ||
− | | 1,4% || | + | | 1,4% || 0% || [[Spindle-shape]]d fibroblastic cells and abundant collagen.<ref name="ParwatePatel2015">{{cite journal|last1=Parwate|first1=Nikhil Sadanand|last2=Patel|first2=Shilpa M.|last3=Arora|first3=Ruchi|last4=Gupta|first4=Monisha|title=Ovarian Fibroma: A Clinico-pathological Study of 23 Cases with Review of Literature|journal=The Journal of Obstetrics and Gynecology of India|volume=66|issue=6|year=2015|pages=460–465|issn=0971-9202|doi=10.1007/s13224-015-0717-6}}</ref> || [[File:Histopathology of an ovarian fibroma.jpg|200px]] |
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! Adult [[Granulosa cell tumour|granulosa cell tumor]] | ! Adult [[Granulosa cell tumour|granulosa cell tumor]] | ||
− | | 1,1% || 100 | + | | 1,1% || Almost 100% || Small, bland, cuboidal to polygonal cells in various patterns.<ref>{{cite web|url=http://www.pathologyoutlines.com/topic/ovarytumorgctadult.html|title=Ovary tumor - Sex cord stromal tumors - Granulosa cell tumor - adult|author=Shahrzad Ehdaivand|website=Pathology Outlines}} Topic Completed: 1 December 2012. Revised: 9 March 2020</ref> || [[File:Granulosa Cell Tumor of the Ovary (5621714007).jpg|200px]] |
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! Other sex cord-stromal tumors | ! Other sex cord-stromal tumors | ||
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!colspan=2| Secondary/metastatic) tumor | !colspan=2| Secondary/metastatic) tumor | ||
− | | 1,7% || 100 | + | | 1,7% || 100% || Usually from [[breast cancer]], [[colon cancer]], [[endometrial cancer]], [[stomach cancer]] or [[cervical cancer]].<ref name=Lee-Jones>{{cite web|url=http://atlasgeneticsoncology.org/Tumors/OvarianTumOverviewID5231.html|title=Ovarian tumours : an overview|author=Lisa Lee-Jones, University of Wales College of Medicine|date=2003-12-01|website=Atlas of Genetics and Cytogenetics in Oncology and Haematology}}</ref> |
|} | |} | ||
{{Bottom}} | {{Bottom}} |
Revision as of 09:24, 17 March 2020
Author:
Mikael Häggström [note 1]
Microscopic evaluation
Look for the most common types of ovarian tumor:
Type | Subtype | Relative incidence[2] | Percent malignant[2] | Comments | Micrograph |
---|---|---|---|---|---|
Germ cell tumor | Mature cystic teratoma | 46,0% | 0.17% to 2%[3] | Cystic, with elements of all 3 germ layers (endoderm, mesoderm and ectoderm).[4] | |
Immature teratoma | 2,5% | 100% | A teratoma that contains anaplastic immature elements, and is often synonymous with malignant teratoma.[5] | ||
Other germ cell tumors | 3,0% | Others mainly include dysgerminoma, yolk sac tumor, struma ovarii and squamous cell carcinoma arising from a dermoid cyst, and malignant mixed germ cell tumor.[2] | |||
Surface epithelial-stromal tumor | Serous tumor | 25,3% | 18.5% | Benign serous tumors of the right ovarian cyst are thinwalled unilocular cysts that are lined by ciliated pseudostratified cuboidal or columnar epithelium.[6] | |
Mucinous tumor | 15,7% | 8.8% | Benign mucinous tumors of the ovary consist of simple, nonstratified columnar epithelium with basally-located hyperchromatic nuclei and resemble gastric foveolar epithelium.[6] | ||
Endometrioid tumor | 1,1% | Almost 100% | Tubular glands, resembling endometrium.[7] | ||
Other surface-epithelial tumors | 1,4% | Others include mainly malignant mixed mullerian tumor, Brenner tumor and mixed epithelial tumor.[2] | |||
Sex cord-stromal tumor | Ovarian fibroma | 1,4% | 0% | Spindle-shaped fibroblastic cells and abundant collagen.[8] | |
Adult granulosa cell tumor | 1,1% | Almost 100% | Small, bland, cuboidal to polygonal cells in various patterns.[9] | ||
Other sex cord-stromal tumors | 0,8% | Others include mainly juvenile granulosa cell tumor, thecoma and sclerosing stromal tumor[2] | |||
Secondary/metastatic) tumor | 1,7% | 100% | Usually from breast cancer, colon cancer, endometrial cancer, stomach cancer or cervical cancer.[10] |
Notes
- ↑ For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.
Main page
References
- ↑ - Vaidya, SA; Kc, S; Sharma, P; Vaidya, S (2014). "Spectrum of ovarian tumors in a referral hospital in Nepal
". Journal of Pathology of Nepal 4 (7): 539–543. doi: . ISSN 2091-0908.
- Minor adjustment for mature cystic teratomas (0.17 to 2% risk of ovarian cancer): Mandal, Shramana; Badhe, Bhawana A. (2012). "Malignant Transformation in a Mature Teratoma with Metastatic Deposits in the Omentum: A Case Report ". Case Reports in Pathology 2012: 1–3. doi: . ISSN 2090-6781. - ↑ 2.0 2.1 2.2 2.3 2.4 Unless otherwise specified in boxes, reference is: Vaidya, SA; Kc, S; Sharma, P; Vaidya, S (2014). "Spectrum of ovarian tumors in a referral hospital in Nepal ". Journal of Pathology of Nepal 4 (7): 539–543. doi: . ISSN 2091-0908.
- ↑ Mandal, Shramana; Badhe, Bhawana A. (2012). "Malignant Transformation in a Mature Teratoma with Metastatic Deposits in the Omentum: A Case Report ". Case Reports in Pathology 2012: 1–3. doi: . ISSN 2090-6781.
- ↑ Hillary Rose Elwood. Skin nonmelanocytic tumor - Other tumors of skin - Benign (mature) cystic teratoma. pathology Outlines. Topic Completed: 1 November 2016. Revised: 4 April 2019
- ↑ Sun, Hang; Ding, Hongxin; Wang, Jianjun; Zhang, Emma; Fang, Yihua; Li, Zhenhua; Yu, Xiao; Wang, Chongren; et al. (2019). "The differences between gonadal and extra-gonadal malignant teratomas in both genders and the effects of chemotherapy ". BMC Cancer 19 (1). doi: . ISSN 1471-2407.
- ↑ 6.0 6.1 Baradwan, Saeed; Alalyani, Haneen; Baradwan, Amira; Baradwan, Afnan; Al-Ghamdi, Maram; Alnemari, Jameel; Al-Jaroudi, Dania (2018). "Bilateral ovarian masses with different histopathology in each ovary ". Clinical Case Reports 6 (5): 784–787. doi: . ISSN 20500904.
- ↑ Shahrzad Ehdaivand. Ovary tumor - Endometrioid tumors - General. Pathology Outlines. Topic Completed: 1 December 2012. Revised: 6 March 2020
- ↑ Parwate, Nikhil Sadanand; Patel, Shilpa M.; Arora, Ruchi; Gupta, Monisha (2015). "Ovarian Fibroma: A Clinico-pathological Study of 23 Cases with Review of Literature ". The Journal of Obstetrics and Gynecology of India 66 (6): 460–465. doi: . ISSN 0971-9202.
- ↑ Shahrzad Ehdaivand. Ovary tumor - Sex cord stromal tumors - Granulosa cell tumor - adult. Pathology Outlines. Topic Completed: 1 December 2012. Revised: 9 March 2020
- ↑ Lisa Lee-Jones, University of Wales College of Medicine (2003-12-01). Ovarian tumours : an overview. Atlas of Genetics and Cytogenetics in Oncology and Haematology.
Image sources