Pancreatic tumor
Author:
Mikael Häggström [note 1]
Microscopic evaluation
Stages of pancreatic intraepithelial neoplasia.[1]
Cancer type | Relative incidence[2] | Microscopy findings[2] | Micrograph | Immunohistochemistry markers[2] | Genetic alterations[2] |
---|---|---|---|---|---|
Pancreatic ductal adenocarcinoma (PDAC) | 90% | Glands and desmoplasia | |||
Pancreatic acinar cell carcinoma (ACC) | 1% to 2% | Granular appearance | |||
Adenosquamous carcinoma | 1% to 4%[3] | Combination of gland-like cells and squamous epithelial cells. | Positive for:
Negative for: |
||
Pancreatic neuroendocrine tumor | 5% | Multiple nests of tumor cells | Gastrinoma | ||
Pre-cancer below for comparison: | |||||
Precancer: Intraductal papillary mucinous neoplasm (IPMN) |
3% | Mucinous epithelial cells.[4] Growth within the pancreatic ducts.[5] |
Further information: Evaluation of tumors
Notes
- ↑ For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.
Main page
References
- ↑ Hackeng WM, Hruban RH, Offerhaus GJ, Brosens LA (2016). "Surgical and molecular pathology of pancreatic neoplasms.
". Diagn Pathol 11 (1): 47. doi: . PMID 27267993. PMC: 4897815. Archived from the original. .
- "This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/)"
- Image title and optimization: Mikael Häggström, M.D. - ↑ 2.0 2.1 2.2 2.3 Unless otherwise specified in boxes, reference is: "Therapeutic Implications of Molecular Subtyping for Pancreatic Cancer ". Oncology 31 (3): 159–66, 168. March 2017. PMID 28299752. Archived from the original. .
- ↑ "Adenosquamous carcinoma of the pancreas: a case report ". Cases Journal 3 (1): 41. February 2010. doi: . PMID 20205828.
- ↑ Diana Agostini-Vulaj. Pancreas – Exocrine tumors / carcinomas – Intraductal papillary mucinous neoplasm (IPMN). Pathology Outlines. Topic Completed: 1 July 2018. Revised: 9 March 2020
- ↑ "Pathologic Evaluation and Reporting of Intraductal Papillary Mucinous Neoplasms of the Pancreas and Other Tumoral Intraepithelial Neoplasms of Pancreatobiliary Tract: Recommendations of Verona Consensus Meeting ". Annals of Surgery 263 (1): 162–77. January 2016. doi: . PMID 25775066.
Image sources