Difference between revisions of "Parathyroid glands"
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File:1814 The Parathyroid Glands.jpg|Location and histology of the parathyroid glands | File:1814 The Parathyroid Glands.jpg|Location and histology of the parathyroid glands | ||
| + | File:Histopathology of parathyroid chief cell hyperplasia.jpg|Parathyroid '''chief cell hyperplasia''': An increase in the parenchymal cell mass,as a result of the proliferation of chief cells, oncocytes, and transitional oncocytes in multiple parathyroid glands.<ref>{{cite journal|last1=Piciucchi|first1=Sara|last2=Barone|first2=Domenico|last3=Gavelli|first3=Giampaolo|last4=Dubini|first4=Alessandra|last5=Oboldi|first5=Devil|last6=Matteuci|first6=Federica|title=Primary Hyperparathyroidism: Imaging to Pathology|journal=Journal of Clinical Imaging Science|volume=2|year=2012|pages=59|issn=2156-7514|doi=10.4103/2156-7514.102053}}<br>- This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.</ref> | ||
File:Parathyroid Adenoma 2 (4702993415).jpg|Parathyroid '''adenoma''', histology | File:Parathyroid Adenoma 2 (4702993415).jpg|Parathyroid '''adenoma''', histology | ||
File:Parathyroid Adenoma, FNA (5691039847).jpg|Parathyroid '''adenoma''', fine needle aspiration | File:Parathyroid Adenoma, FNA (5691039847).jpg|Parathyroid '''adenoma''', fine needle aspiration | ||
Revision as of 10:23, 21 July 2020
Author:
Mikael Häggström [note 1]
Contents
Autopsy
Optionally for a comprehensive autopsy, or where there is suspicion of parathyroid pathology, an effort is made to find the parathyroid glands, and inspect them for general or focal hyper-/neoplasia.
Microscopic evaluation
Look for the main findings, which are:
- Hyperplastic glands, often nodular and asymmetric on inspection, and microscopy frequently show increased number of oxyphil cells.[1]
- Parathyroid adenoma.[1]
Serum calcium levels are generally elevated in patients with adenomas or hyperplastic glands containing large nodules, and often correlates with nephrosclerosis.[1]
Location and histology of the parathyroid glands
Parathyroid chief cell hyperplasia: An increase in the parenchymal cell mass,as a result of the proliferation of chief cells, oncocytes, and transitional oncocytes in multiple parathyroid glands.[2]
Parathyroid adenoma, histology
Parathyroid adenoma, fine needle aspiration
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See also
Notes
- ↑ For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.
Main page
References
- ↑ 1.0 1.1 1.2 Åkerström, G.; Rudberg, C.; Grimelius, L.; Bergström, R.; Johansson, H.; Ljunghall, S.; Rastad, J. (1986). "Histologic parathyroid abnormalities in an autopsy series ". Human Pathology 17 (5): 520–527. doi:. ISSN 00468177.
- ↑ Piciucchi, Sara; Barone, Domenico; Gavelli, Giampaolo; Dubini, Alessandra; Oboldi, Devil; Matteuci, Federica (2012). "Primary Hyperparathyroidism: Imaging to Pathology
". Journal of Clinical Imaging Science 2: 59. doi:. ISSN 2156-7514.
- This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Image sources
