Difference between revisions of "Parathyroid glands"

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==Microscopic evaluation==
 
==Microscopic evaluation==
Look for the main findings, which are:
+
Look for the most common significant findings, which are:
 
*'''Hyperplastic glands''', often nodular and asymmetric on inspection, and microscopy frequently show increased number of oxyphil cells.<ref name="ÅkerströmRudberg1986">{{cite journal|last1=Åkerström|first1=G.|last2=Rudberg|first2=C.|last3=Grimelius|first3=L.|last4=Bergström|first4=R.|last5=Johansson|first5=H.|last6=Ljunghall|first6=S.|last7=Rastad|first7=J.|title=Histologic parathyroid abnormalities in an autopsy series|journal=Human Pathology|volume=17|issue=5|year=1986|pages=520–527|issn=00468177|doi=10.1016/S0046-8177(86)80043-0}}</ref>
 
*'''Hyperplastic glands''', often nodular and asymmetric on inspection, and microscopy frequently show increased number of oxyphil cells.<ref name="ÅkerströmRudberg1986">{{cite journal|last1=Åkerström|first1=G.|last2=Rudberg|first2=C.|last3=Grimelius|first3=L.|last4=Bergström|first4=R.|last5=Johansson|first5=H.|last6=Ljunghall|first6=S.|last7=Rastad|first7=J.|title=Histologic parathyroid abnormalities in an autopsy series|journal=Human Pathology|volume=17|issue=5|year=1986|pages=520–527|issn=00468177|doi=10.1016/S0046-8177(86)80043-0}}</ref>
 
*Parathyroid '''adenoma'''.<ref name="ÅkerströmRudberg1986"/>
 
*Parathyroid '''adenoma'''.<ref name="ÅkerströmRudberg1986"/>
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===Microscopy report===
 
===Microscopy report===
 
Normal example:
 
Normal example:
*Sections show <<1, 2, 3, 4>> parathyroid glands with no signs of hyperplasia or tumor.
+
*Sections show <<1, 2, 3, 4>> parathyroid glands with no focal changes or signs of hyperplasia.
  
 
==See also==
 
==See also==
 
*[[Thyroid]]
 
*[[Thyroid]]
 
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Latest revision as of 07:49, 1 October 2020

Author: Mikael Häggström [notes 1]

Autopsy

Optionally for a comprehensive autopsy, or where there is suspicion of parathyroid pathology, an effort is made to find the parathyroid glands, and inspect them for general or focal hyper-/neoplasia.

Microscopic evaluation

Look for the most common significant findings, which are:

  • Hyperplastic glands, often nodular and asymmetric on inspection, and microscopy frequently show increased number of oxyphil cells.[1]
  • Parathyroid adenoma.[1]

Serum calcium levels are generally elevated in patients with adenomas or hyperplastic glands containing large nodules, and often correlates with nephrosclerosis.[1]

Microscopy report

Normal example:

  • Sections show <<1, 2, 3, 4>> parathyroid glands with no focal changes or signs of hyperplasia.

See also

Notes

  1. For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.

Main page

References

  1. 1.0 1.1 1.2 Åkerström, G.; Rudberg, C.; Grimelius, L.; Bergström, R.; Johansson, H.; Ljunghall, S.; Rastad, J. (1986). "Histologic parathyroid abnormalities in an autopsy series ". Human Pathology 17 (5): 520–527. doi:10.1016/S0046-8177(86)80043-0. ISSN 00468177. 
  2. Piciucchi, Sara; Barone, Domenico; Gavelli, Giampaolo; Dubini, Alessandra; Oboldi, Devil; Matteuci, Federica (2012). "Primary Hyperparathyroidism: Imaging to Pathology ". Journal of Clinical Imaging Science 2: 59. doi:10.4103/2156-7514.102053. ISSN 2156-7514. 
    - This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.