Difference between revisions of "Peritoneal fluid"

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==Evaluation==
 
==Evaluation==
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Look mainly for malignancy:
 
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File:Pap stain of adenocarcinoma in peritoneal fluid.jpg|Adenocarcinoma in peritoneal fluid, Pap stain. The typical features of adenocarcinoma seen are high nuclear-to-cytoplasm ratio and prominent nucleoli.
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File:Pap stain of adenocarcinoma in peritoneal fluid.png|Adenocarcinoma in peritoneal fluid with typical features, Pap stain. Vacuoles may be seen in both serous and mucinous adenocarcinomas.
 
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When finding adenocarcinoma in pleural fluid in a female, and there is no other specimen, preferably perform immunostaining including PAX-8 and WT-1 to confirm a Müllerian tract origin. Also consider p53 to distinguish low-grade (wild-type staining) from high grade (aberrant staining) serous ovarian carcinoma.
 
When finding adenocarcinoma in pleural fluid in a female, and there is no other specimen, preferably perform immunostaining including PAX-8 and WT-1 to confirm a Müllerian tract origin. Also consider p53 to distinguish low-grade (wild-type staining) from high grade (aberrant staining) serous ovarian carcinoma.
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===Reporting===
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Example report:
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{|class=wikitable
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| Peritoneal fluid:
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*Positive for malignant cells.
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*Adenocarcinoma.
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Comment: Immunohistochemistry was performed, and showed tumor cells positive for PAX-8 and WT-1, and negative (null phenotype) for p53. These findings are consistent with a tumor of Müllerian (serous) origin.
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Revision as of 15:32, 14 September 2022

Author: Mikael Häggström, M.D. [note 1]

Evaluation

Look mainly for malignancy:

When finding adenocarcinoma in pleural fluid in a female, and there is no other specimen, preferably perform immunostaining including PAX-8 and WT-1 to confirm a Müllerian tract origin. Also consider p53 to distinguish low-grade (wild-type staining) from high grade (aberrant staining) serous ovarian carcinoma.

Reporting

Example report:

Peritoneal fluid:
  • Positive for malignant cells.
  • Adenocarcinoma.

Comment: Immunohistochemistry was performed, and showed tumor cells positive for PAX-8 and WT-1, and negative (null phenotype) for p53. These findings are consistent with a tumor of Müllerian (serous) origin.

Notes

  1. For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.

Main page

References


Image sources