Difference between revisions of "Peritoneal fluid"
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==Evaluation== | ==Evaluation== | ||
+ | Look mainly for malignancy: | ||
<gallery mode=packed heights=190> | <gallery mode=packed heights=190> | ||
− | File:Pap stain of adenocarcinoma in peritoneal fluid. | + | File:Pap stain of adenocarcinoma in peritoneal fluid.png|Adenocarcinoma in peritoneal fluid with typical features, Pap stain. Vacuoles may be seen in both serous and mucinous adenocarcinomas. |
</gallery> | </gallery> | ||
When finding adenocarcinoma in pleural fluid in a female, and there is no other specimen, preferably perform immunostaining including PAX-8 and WT-1 to confirm a Müllerian tract origin. Also consider p53 to distinguish low-grade (wild-type staining) from high grade (aberrant staining) serous ovarian carcinoma. | When finding adenocarcinoma in pleural fluid in a female, and there is no other specimen, preferably perform immunostaining including PAX-8 and WT-1 to confirm a Müllerian tract origin. Also consider p53 to distinguish low-grade (wild-type staining) from high grade (aberrant staining) serous ovarian carcinoma. | ||
+ | |||
+ | ===Reporting=== | ||
+ | Example report: | ||
+ | {|class=wikitable | ||
+ | | Peritoneal fluid: | ||
+ | *Positive for malignant cells. | ||
+ | *Adenocarcinoma. | ||
+ | Comment: Immunohistochemistry was performed, and showed tumor cells positive for PAX-8 and WT-1, and negative (null phenotype) for p53. These findings are consistent with a tumor of Müllerian (serous) origin. | ||
+ | |} | ||
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Revision as of 15:32, 14 September 2022
Author:
Mikael Häggström, M.D. [note 1]
Evaluation
Look mainly for malignancy:
When finding adenocarcinoma in pleural fluid in a female, and there is no other specimen, preferably perform immunostaining including PAX-8 and WT-1 to confirm a Müllerian tract origin. Also consider p53 to distinguish low-grade (wild-type staining) from high grade (aberrant staining) serous ovarian carcinoma.
Reporting
Example report:
Peritoneal fluid:
Comment: Immunohistochemistry was performed, and showed tumor cells positive for PAX-8 and WT-1, and negative (null phenotype) for p53. These findings are consistent with a tumor of Müllerian (serous) origin. |
Notes
- ↑ For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.
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References
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