Peritoneal fluid
Revision as of 15:32, 14 September 2022 by Mikael Häggström (talk | contribs) (→Evaluation: +Comment)
Author:
Mikael Häggström, M.D. [note 1]
Contents
Evaluation
Look mainly for malignancy:
Adenocarcinoma in peritoneal fluid with typical features, Pap stain. Vacuoles may be seen in both serous and mucinous adenocarcinomas.
When finding adenocarcinoma in pleural fluid in a female, and there is no other specimen, preferably perform immunostaining including PAX-8 and WT-1 to confirm a Müllerian tract origin. Also consider p53 to distinguish low-grade (wild-type staining) from high grade (aberrant staining) serous ovarian carcinoma.
Reporting
Example report:
Peritoneal fluid:
Comment: Immunohistochemistry was performed, and showed tumor cells positive for PAX-8 and WT-1, and negative (null phenotype) for p53. These findings are consistent with a tumor of Müllerian (serous) origin. |
Notes
- ↑ For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.
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References
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