Peritoneal fluid

From patholines.org
Revision as of 15:41, 18 October 2022 by Mikael Häggström (talk | contribs) (→‎Evaluation: . Wright's stain)
(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)
Jump to navigation Jump to search

Author: Mikael Häggström, M.D. [note 1]

Evaluation

Look mainly for malignancy.

When finding adenocarcinoma in pleural fluid in a female, and there is no other specimen, preferably perform immunostaining including PAX-8 and WT-1 to confirm a Müllerian tract origin. Also consider p53 to distinguish low-grade (wild-type staining) from high grade (aberrant staining) serous ovarian carcinoma.

Reporting

Example report:

Peritoneal fluid:
  • Positive for malignant cells.
  • Adenocarcinoma.

Comment: Immunohistochemistry was performed, and showed tumor cells positive for PAX-8 and WT-1, and negative (null phenotype) for p53. These findings are consistent with a tumor of Müllerian (serous) origin.

Notes

  1. For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.

Main page

References

  1. Image by Mikael Häggström. MD.
    Reference for findings and causes: . Reactive Mesothelial Cells. LabCE.
  2. Image by Mikael Häggström
    - . Mesothelial cytopathology. Libre Pathology. Retrieved on 2022-10-18.
    - Shidham VB, Layfield LJ (2021). "Introduction to the second edition of 'Diagnostic Cytopathology of Serous Fluids' as CytoJournal Monograph (CMAS) in Open Access. ". Cytojournal 18: 30. doi:10.25259/CMAS_02_01_2021. PMID 35126608. 

Image sources