Difference between revisions of "Pigmented macrophages of the lung"

From patholines.org
Jump to navigation Jump to search
m (e)
(Tabled)
Line 3: Line 3:
 
|author2=
 
|author2=
 
}}
 
}}
When seeing pigmented macrophages of the lung, look for:
+
When seeing pigmented macrophages of the lung, categorize as follows:
<gallery mode=packed heights=200>
+
 
File:Histopathology of anthracotic macrophage in lung, annotated.jpg|Signs of anthracosis (black arrow shows interstitial anthracotic pigment). Nearby macrophages (white arrow) can be presumed to contain anthracotic pigment. Reporting is optional in mild cases in the elderly.
+
{|class=wikitable
File:Histopathology of pulmonary congestion and siderophages.jpg|Signs of cardiac failure ({{Further|Lung autopsy|linebreak=no}})
+
! Disease !! Macrophages !! Pigment appearance (HE stain) !! Associated medical history !! Image !! Image comment
</gallery>
+
|-
 +
! Anthracosis
 +
|  || Black-brown
 +
|
 +
*Age and urban dwelling.<ref name="robspath">{{cite book | title=Robbins Pathologic Basis of Disease| last=Cotran|author2=Kumar, Collins| publisher=W.B Saunders Company| location=Philadelphia| isbn=978-0-7216-7335-6| year=1999}}</ref>
 +
*Coal workers<ref>{{cite journal |author=Morgan WK |title=Industrial bronchitis |journal=Br J Ind Med |volume=35 |issue=4 |pages=285–91 |date=November 1978 |pmid=367424 |pmc=1008445 }}</ref>
 +
| [[File:Histopathology of anthracotic macrophage in lung, annotated.jpg|200px]]
 +
| Black arrow shows interstitial anthracotic pigment. Nearby macrophages (white arrow) can be presumed to contain anthracotic pigment. Reporting is optional in mild cases in the elderly.
 +
|-
 +
! Respiratory bronchiolitis
 +
| "Smoker's macrophages"
 +
| Yellow to light brown and finely granular<ref>{{cite web|url=https://www.pathologyoutlines.com/topic/lungnontumorrespbronchiolitis.html|title=Lung - Other interstitial pneumonitis / fibrosis - Respiratory bronchiolitis|author=William Perry, M.D., M.P.H., Kristine Konopka, M.D.}} Topic Completed: 1 July 2020. Minor changes: 1 July 2020.</ref> || Tobacco smoking
 +
| [[File:Histopathology of respiratory bronchiolitis.jpg|200px]]
 +
| Smoker's macrophages (arrow); mild interstitial lymphocytic infiltrate and mild fibrosis (arrowhead)<ref>{{cite journal|last1=Sousa|first1=Célia|last2=Rodrigues|first2=Márcio|last3=Carvalho|first3=André|last4=Viamonte|first4=Bárbara|last5=Cunha|first5=Rui|last6=Guimarães|first6=Susana|last7=de Moura|first7=Conceição Souto|last8=Morais|first8=António|last9=Pereira|first9=José Miguel|title=Diffuse smoking-related lung diseases: insights from a radiologic-pathologic correlation|journal=Insights into Imaging|volume=10|issue=1|year=2019|issn=1869-4101|doi=10.1186/s13244-019-0765-z}}<br>- This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/)</ref>
 +
|-
 +
! '''Heart failure'''
 +
| Siderophages || Brown granules<ref>{{cite web|url=https://webpath.med.utah.edu/LUNGHTML/LUNG101.html|title=Pulmonary congestion|website=The Internet Pathology Laboratory for Medical Education, Hosted By The University of Utah Eccles Health Sciences Library|author=Edward C. Klatt|accessddate=2021-02-16}}</ref>
 +
*Heart failure
 +
*Pulmonary hemorrhage
 +
| [[File:Histopathology of pulmonary congestion and siderophages.jpg|200px]]
 +
|}
 
{{Bottom}}
 
{{Bottom}}

Revision as of 17:37, 16 February 2021

Author: Mikael Häggström [note 1]
When seeing pigmented macrophages of the lung, categorize as follows:

Disease Macrophages Pigment appearance (HE stain) Associated medical history Image Image comment
Anthracosis Black-brown
  • Age and urban dwelling.[1]
  • Coal workers[2]
Histopathology of anthracotic macrophage in lung, annotated.jpg Black arrow shows interstitial anthracotic pigment. Nearby macrophages (white arrow) can be presumed to contain anthracotic pigment. Reporting is optional in mild cases in the elderly.
Respiratory bronchiolitis "Smoker's macrophages" Yellow to light brown and finely granular[3] Tobacco smoking Histopathology of respiratory bronchiolitis.jpg Smoker's macrophages (arrow); mild interstitial lymphocytic infiltrate and mild fibrosis (arrowhead)[4]
Heart failure Siderophages Brown granules[5]
  • Heart failure
  • Pulmonary hemorrhage
Histopathology of pulmonary congestion and siderophages.jpg

Notes

  1. For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.

Main page

References

  1. Cotran; Kumar, Collins (1999). Robbins Pathologic Basis of Disease . Philadelphia: W.B Saunders Company. ISBN 978-0-7216-7335-6. 
  2. Morgan WK (November 1978). "Industrial bronchitis ". Br J Ind Med 35 (4): 285–91. PMID 367424. 
  3. William Perry, M.D., M.P.H., Kristine Konopka, M.D.. Lung - Other interstitial pneumonitis / fibrosis - Respiratory bronchiolitis. Topic Completed: 1 July 2020. Minor changes: 1 July 2020.
  4. Sousa, Célia; Rodrigues, Márcio; Carvalho, André; Viamonte, Bárbara; Cunha, Rui; Guimarães, Susana; de Moura, Conceição Souto; Morais, António; et al. (2019). "Diffuse smoking-related lung diseases: insights from a radiologic-pathologic correlation ". Insights into Imaging 10 (1). doi:10.1186/s13244-019-0765-z. ISSN 1869-4101. 
    - This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/)
  5. Edward C. Klatt. Pulmonary congestion. The Internet Pathology Laboratory for Medical Education, Hosted By The University of Utah Eccles Health Sciences Library.

Image sources