Difference between revisions of "Pituitary"

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File:Pie chart of incidences of silent pituitary adenomas.png|Incidences of silent pituitary adenomas.<ref>{{cite journal|last1=Drummond|first1=Juliana|last2=Roncaroli|first2=Federico|last3=Grossman|first3=Ashley B|last4=Korbonits|first4=Márta|title=Clinical and Pathological Aspects of Silent Pituitary Adenomas|journal=The Journal of Clinical Endocrinology & Metabolism|volume=104|issue=7|year=2019|pages=2473–2489|issn=0021-972X|doi=10.1210/jc.2018-00688}}<br>- "This article has been published under the terms of the Creative Commons Attribution License (CC BY; https://creativecommons.org/licenses/by/4.0/)"</ref>
 
File:Pie chart of incidences of silent pituitary adenomas.png|Incidences of silent pituitary adenomas.<ref>{{cite journal|last1=Drummond|first1=Juliana|last2=Roncaroli|first2=Federico|last3=Grossman|first3=Ashley B|last4=Korbonits|first4=Márta|title=Clinical and Pathological Aspects of Silent Pituitary Adenomas|journal=The Journal of Clinical Endocrinology & Metabolism|volume=104|issue=7|year=2019|pages=2473–2489|issn=0021-972X|doi=10.1210/jc.2018-00688}}<br>- "This article has been published under the terms of the Creative Commons Attribution License (CC BY; https://creativecommons.org/licenses/by/4.0/)"</ref>
 
File:Histopathology of eosinophilic silent gonadotroph pituitary adenoma.jpg|A silent gonadotroph pituitary adenoma which is in this case is eosinophilic (contrary to normal, basophilic, gonadotroph cells).<ref>{{cite journal|last1=Gaballa|first1=Salem|last2=Lindsay|first2=Jane|last3=AlJaf|first3=Avan|last4=Hlaing|first4=Kyaw M|last5=Patel|first5=Kashyap|title=Acute Unilateral Oculomotor Nerve Palsy as the Initial Presenting Sign of Nonfunctioning Apoplectic Gonadotroph Adenoma|journal=Cureus|year=2020|issn=2168-8184|doi=10.7759/cureus.8819}}<br>- "This is an open access article distributed under the terms of the Creative Commons Attribution License CC-BY 4.0"</ref>
 
File:Histopathology of eosinophilic silent gonadotroph pituitary adenoma.jpg|A silent gonadotroph pituitary adenoma which is in this case is eosinophilic (contrary to normal, basophilic, gonadotroph cells).<ref>{{cite journal|last1=Gaballa|first1=Salem|last2=Lindsay|first2=Jane|last3=AlJaf|first3=Avan|last4=Hlaing|first4=Kyaw M|last5=Patel|first5=Kashyap|title=Acute Unilateral Oculomotor Nerve Palsy as the Initial Presenting Sign of Nonfunctioning Apoplectic Gonadotroph Adenoma|journal=Cureus|year=2020|issn=2168-8184|doi=10.7759/cureus.8819}}<br>- "This is an open access article distributed under the terms of the Creative Commons Attribution License CC-BY 4.0"</ref>
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===Microscopy report===
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In normal autopsy:
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{|class=wikitable
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| Adenohypophysis and neurohypophysis with no focal changes.
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|}
 
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Revision as of 15:10, 18 November 2020

Author: Mikael Häggström [note 1]

Microscopic evaluation

  • Look for cellular expansions
  • If present, distinguish it as hyperplasia or neoplasia. If uncertain, by using reticulin immunohistochemistry, hyperplasia will show a preserved reticulin meshwork, whereas pituitary adenomas have disruption of it.[1]
  • For adenomas, unless otherwise indicated by the medical history, will generally by definition be of the silent type. Basophilic or acidophilic staining may give a clue about the subtype, but immunohistochemistry is generally required.

Microscopy report

In normal autopsy:

Adenohypophysis and neurohypophysis with no focal changes.

Notes

  1. For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.

Main page

References

  1. Al-Brahim, N Y Y; Asa, S L (2006). "My approach to pathology of the pituitary gland ". Journal of Clinical Pathology 59 (12): 1245–1253. doi:10.1136/jcp.2005.031187. ISSN 0021-9746. 
  2. Drummond, Juliana; Roncaroli, Federico; Grossman, Ashley B; Korbonits, Márta (2019). "Clinical and Pathological Aspects of Silent Pituitary Adenomas ". The Journal of Clinical Endocrinology & Metabolism 104 (7): 2473–2489. doi:10.1210/jc.2018-00688. ISSN 0021-972X. 
    - "This article has been published under the terms of the Creative Commons Attribution License (CC BY; https://creativecommons.org/licenses/by/4.0/)"
  3. Gaballa, Salem; Lindsay, Jane; AlJaf, Avan; Hlaing, Kyaw M; Patel, Kashyap (2020). "Acute Unilateral Oculomotor Nerve Palsy as the Initial Presenting Sign of Nonfunctioning Apoplectic Gonadotroph Adenoma ". Cureus. doi:10.7759/cureus.8819. ISSN 2168-8184. 
    - "This is an open access article distributed under the terms of the Creative Commons Attribution License CC-BY 4.0"

Image sources