Stomach biopsy for Helicobacter pylori
- Helicobacter pylori-like bacteria in the lumen, as curved, spirochete-like bacteria, generally in the superficial mucus layer and along microvilli of epithelial cells.
- Associated inflammation, typically a chronic form of gastritis with germinal centers (follicular gastritis), and plasma cells in lamina propria.[notes 2] There should be at least 3 plasma cells facing each other to make a diagnosis of chronic gastritis.
Perform immunohistochemistry for H. pylori if there is gastritis but uncertainty whether H. pylori-like bacteria are seen.
Chronic gastritis without H. pylori-like organisms should be described as non-specific:
|Mild chronic gastritis, which is non-specific.|
Negative for H. pylori-like organisms on H&E stain.
- For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.
- Plasma cells and lymphocytes are normally found in the lamina propria of the small and large intestine, but is abnormal in the stomach.
- Elliot Weisenberg. Stomach - Infections - Helicobacter pylori. Pathology Outlines. Topic Completed: 1 August 2012. Minor changes: 1 September 2020