Difference between revisions of "Template:Brain - autopsy gross processing"

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*'''Weight''' the brain. Overall normal range (95% prediction interval) is 1100 to 1700 g,<ref name="GovenderLazarus2018">{{cite journal|last1=Govender|first1=S|last2=Lazarus|first2=L|last3=De-Gama|first3=B. Z|last4=Satyapal|first4=K. S|title=Post-Mortem Brain Weight Reference Range for a Select South African Population|journal=International Journal of Morphology|volume=36|issue=3|year=2018|pages=915–920|issn=0717-9502|doi=10.4067/S0717-95022018000300915}}</ref> +60g for males and -60g for females.<ref>{{Cite book|url = https://books.google.com/books?id=u1bwQj7qdsYC|title = Reader in Gender archaeology|access-date = 2014-09-21|publisher = Routlegde|author1=Kelley Hays |author2=David S. |isbn = 9780415173605|year = 1998}}</ref>
 
*'''Inspect''': Grooves indicating herniation? Hemorrhages?
 
*'''Inspect''': Grooves indicating herniation? Hemorrhages?
 
*Dissect the '''basilar artery''' and '''circle of Willis''', either before or after separation from the brain.<ref group="notes">The arteries of the skull base are preferably dissected after separation from the brain if there is a need to demonstrate the case.</ref> Look mainly for thromboses.
 
*Dissect the '''basilar artery''' and '''circle of Willis''', either before or after separation from the brain.<ref group="notes">The arteries of the skull base are preferably dissected after separation from the brain if there is a need to demonstrate the case.</ref> Look mainly for thromboses.

Revision as of 17:35, 5 August 2021

Author: Mikael Häggström [note 1]
edit

  • Weight the brain. Overall normal range (95% prediction interval) is 1100 to 1700 g,[1] +60g for males and -60g for females.[2]
  • Inspect: Grooves indicating herniation? Hemorrhages?
  • Dissect the basilar artery and circle of Willis, either before or after separation from the brain.[notes 1] Look mainly for thromboses.
  • Separate the brainstem, cerebellum and cerebrum, which may be done by first separating the former two together from the cerebrum.
Normal brain versus in Alzheimer's disease.
  • Slice each part, looking for hemorrhages and/or infarcts.
  • For the cerebrum, cut it into slices about 1 cm thick. It can be done from frontal to occipital, or by starting coronally into two halves at the level of the mammillary bodies and continuing in each direction from there.
  • At least in people aged over 65-75 years of age {{or with suggestive history}}, look for signs of Alzhemier's disease (see picture).

Notes

  1. The arteries of the skull base are preferably dissected after separation from the brain if there is a need to demonstrate the case.
  1. For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.

Main page

References

  1. Govender, S; Lazarus, L; De-Gama, B. Z; Satyapal, K. S (2018). "Post-Mortem Brain Weight Reference Range for a Select South African Population ". International Journal of Morphology 36 (3): 915–920. doi:10.4067/S0717-95022018000300915. ISSN 0717-9502. 
  2. Kelley Hays; David S. (1998). Reader in Gender archaeology . Routlegde. ISBN 9780415173605. Retrieved on 2014-09-21. 

Image sources