Difference between revisions of "Template:Breast cancer staging"
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====Regional Lymph Nodes (N)==== | ====Regional Lymph Nodes (N)==== | ||
− | Lymph '''N'''ode:{{#ifeq:{{PAGENAME}}|Invasive lobular carcinoma| When lymph nodes are submitted together with a biopsy or excision of a suspected or previously confirmed invasive lobular carcinoma | + | Lymph '''N'''ode:{{#ifeq:{{PAGENAME}}|Invasive lobular carcinoma| When sentinel lymph nodes are submitted together with a biopsy or excision of a suspected or previously confirmed invasive lobular carcinoma, and you don't see any involvement on the H&E stain, order immunostain for CK AE1/AE3 in order to visualize otherwise occult lymph node involvement.<ref name="pmid12610108">{{cite journal| author=Chandler IP, Oommen R, Lawson CW| title=Invasive lobular carcinoma and cytokeratin immunohistochemistry: an audit. | journal=J Clin Pathol | year= 2003 | volume= 56 | issue= 3 | pages= 240 | pmid=12610108 | doi=10.1136/jcp.56.3.240 | pmc=1769908 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12610108 }} </ref> However, this is not mandatory for invasive carcinoma with lobular features, or non-sentinel lymph nodes.<P>| }}The lymph node values depend on the number, size and location of breast cancer cell deposits in various regional lymph nodes, such as the armpit (axillary lymph nodes), the collar area (supraclavicular lymph nodes), and inside the chest (internal mammary lymph nodes.)<ref name="pmid3347753">{{cite journal |vauthors=Scatarige JC, Fishman EK, Zinreich ES, Brem RF, Almaraz R |title=Internal mammary lymphadenopathy in breast carcinoma: CT appraisal of anatomic distribution |journal=Radiology |volume=167 |issue=1 |pages=89–91 |date=April 1988 |pmid=3347753 |doi= 10.1148/radiology.167.1.3347753|url=}}</ref><ref name="pmid2217975">{{cite journal |vauthors=Scatarige JC, Boxen I, Smathers RL |title=Internal mammary lymphadenopathy: imaging of a vital lymphatic pathway in breast cancer |journal=Radiographics |volume=10 |issue=5 |pages=857–70 |date=September 1990 |pmid=2217975 |doi= 10.1148/radiographics.10.5.2217975|url=}}</ref> Each stage is as follows:<ref name=Alkabban2019/> |
*N0: There is some nuance to the official definitions for N0 disease, which includes: | *N0: There is some nuance to the official definitions for N0 disease, which includes: | ||
:* N0(i+) : Isolated Tumor Cell clusters (ITC),<ref name=Stanford/> which are small clusters of cells not greater than 0.2 mm, or single tumor cells, or a cluster of fewer than 200 cells in a single histologic cross-section, whether detected by routine histology or [[immunohistochemistry]]; | :* N0(i+) : Isolated Tumor Cell clusters (ITC),<ref name=Stanford/> which are small clusters of cells not greater than 0.2 mm, or single tumor cells, or a cluster of fewer than 200 cells in a single histologic cross-section, whether detected by routine histology or [[immunohistochemistry]]; |
Latest revision as of 11:58, 1 March 2022
Contents
Staging
Stage by the TNM system as follows in sections below.
Also, look for any angiolymphatic invasion. If present, check whether it reaches outside the tumor, and if so, how far.[1] Give greatest dimension (,or 3 dimensions, generally by adding up the estimated thicknesses of involved slices)).[1]
Primary Tumor (T)Tumor – Depends on the tumor at the primary site of origin, as follows:[2]
Regional Lymph Nodes (N)Lymph Node: The lymph node values depend on the number, size and location of breast cancer cell deposits in various regional lymph nodes, such as the armpit (axillary lymph nodes), the collar area (supraclavicular lymph nodes), and inside the chest (internal mammary lymph nodes.)[3][4] Each stage is as follows:[2]
Critical numbers of involved nodes: 1-3, 4-9, and 10 and over. Note any extranodal extension.[1]
Distant Metastases (M)
Overall stageA combination of T, N and M, as follows:[2]
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Notes
Main page
References
- ↑ 1.0 1.1 1.2 1.3 1.4 . Infiltrating Ductal Carcinoma of the Breast (Carcinoma of No Special Type). Stanford Medical School. Retrieved on 2019-10-02.
- ↑ 2.0 2.1 2.2 Originally copied from Fadi M. Alkabban; Troy Ferguson. Cancer, Breast. National Center for Biotechnology Information. Last Update: June 4, 2019. Creative Commons Attribution 4.0 International License
- ↑ "Internal mammary lymphadenopathy in breast carcinoma: CT appraisal of anatomic distribution ". Radiology 167 (1): 89–91. April 1988. doi: . PMID 3347753.
- ↑ "Internal mammary lymphadenopathy: imaging of a vital lymphatic pathway in breast cancer ". Radiographics 10 (5): 857–70. September 1990. doi: . PMID 2217975.
Image sources