https://patholines.org/index.php?title=Template:Breast_cancer_staging&feed=atom&action=history
Template:Breast cancer staging - Revision history
2024-03-28T18:28:40Z
Revision history for this page on the wiki
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https://patholines.org/index.php?title=Template:Breast_cancer_staging&diff=4875&oldid=prev
Mikael Häggström: /* Regional Lymph Nodes (N) */ Or non-sentinel
2022-03-01T15:58:34Z
<p><span dir="auto"><span class="autocomment">Regional Lymph Nodes (N): </span> Or non-sentinel</span></p>
<table class="diff diff-contentalign-left" data-mw="interface">
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<td colspan="2" style="background-color: #fff; color: #222; text-align: center;">← Older revision</td>
<td colspan="2" style="background-color: #fff; color: #222; text-align: center;">Revision as of 15:58, 1 March 2022</td>
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<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>====Regional Lymph Nodes (N)====</div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>====Regional Lymph Nodes (N)====</div></td></tr>
<tr><td class='diff-marker'>−</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>Lymph '''N'''ode:{{#ifeq:{{PAGENAME}}|Invasive lobular carcinoma|&nbsp;When lymph nodes are submitted together with a biopsy or excision of a suspected or previously confirmed invasive lobular carcinoma <del class="diffchange diffchange-inline">(but not necessarily invasive carcinoma with lobular features)</del>, and you don't see any involvement on the H&E stain, order immunostain for CK AE1/AE3 in order to visualize otherwise occult lymph node involvement.<ref name="pmid12610108">{{cite journal| author=Chandler IP, Oommen R, Lawson CW| title=Invasive lobular carcinoma and cytokeratin immunohistochemistry: an audit. | journal=J Clin Pathol | year= 2003 | volume= 56 | issue= 3 | pages= 240 | pmid=12610108 | doi=10.1136/jcp.56.3.240 | pmc=1769908 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12610108 }} </ref><P>|&nbsp;}}The lymph node values depend on the number, size and location of breast cancer cell deposits in various regional lymph nodes, such as the armpit (axillary lymph nodes), the collar area (supraclavicular lymph nodes), and inside the chest (internal mammary lymph nodes.)<ref name="pmid3347753">{{cite journal |vauthors=Scatarige JC, Fishman EK, Zinreich ES, Brem RF, Almaraz R |title=Internal mammary lymphadenopathy in breast carcinoma: CT appraisal of anatomic distribution |journal=Radiology |volume=167 |issue=1 |pages=89–91 |date=April 1988 |pmid=3347753 |doi= 10.1148/radiology.167.1.3347753|url=}}</ref><ref name="pmid2217975">{{cite journal |vauthors=Scatarige JC, Boxen I, Smathers RL |title=Internal mammary lymphadenopathy: imaging of a vital lymphatic pathway in breast cancer |journal=Radiographics |volume=10 |issue=5 |pages=857–70 |date=September 1990 |pmid=2217975 |doi= 10.1148/radiographics.10.5.2217975|url=}}</ref> Each stage is as follows:<ref name=Alkabban2019/></div></td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>Lymph '''N'''ode:{{#ifeq:{{PAGENAME}}|Invasive lobular carcinoma|&nbsp;When <ins class="diffchange diffchange-inline">sentinel </ins>lymph nodes are submitted together with a biopsy or excision of a suspected or previously confirmed invasive lobular carcinoma, and you don't see any involvement on the H&E stain, order immunostain for CK AE1/AE3 in order to visualize otherwise occult lymph node involvement.<ref name="pmid12610108">{{cite journal| author=Chandler IP, Oommen R, Lawson CW| title=Invasive lobular carcinoma and cytokeratin immunohistochemistry: an audit. | journal=J Clin Pathol | year= 2003 | volume= 56 | issue= 3 | pages= 240 | pmid=12610108 | doi=10.1136/jcp.56.3.240 | pmc=1769908 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12610108 }} </ref> <ins class="diffchange diffchange-inline">However, this is not mandatory for invasive carcinoma with lobular features, or non-sentinel lymph nodes.</ins><P>|&nbsp;}}The lymph node values depend on the number, size and location of breast cancer cell deposits in various regional lymph nodes, such as the armpit (axillary lymph nodes), the collar area (supraclavicular lymph nodes), and inside the chest (internal mammary lymph nodes.)<ref name="pmid3347753">{{cite journal |vauthors=Scatarige JC, Fishman EK, Zinreich ES, Brem RF, Almaraz R |title=Internal mammary lymphadenopathy in breast carcinoma: CT appraisal of anatomic distribution |journal=Radiology |volume=167 |issue=1 |pages=89–91 |date=April 1988 |pmid=3347753 |doi= 10.1148/radiology.167.1.3347753|url=}}</ref><ref name="pmid2217975">{{cite journal |vauthors=Scatarige JC, Boxen I, Smathers RL |title=Internal mammary lymphadenopathy: imaging of a vital lymphatic pathway in breast cancer |journal=Radiographics |volume=10 |issue=5 |pages=857–70 |date=September 1990 |pmid=2217975 |doi= 10.1148/radiographics.10.5.2217975|url=}}</ref> Each stage is as follows:<ref name=Alkabban2019/></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>*N0: There is some nuance to the official definitions for N0 disease, which includes:</div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>*N0: There is some nuance to the official definitions for N0 disease, which includes:</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>:* N0(i+) : Isolated Tumor Cell clusters (ITC),<ref name=Stanford/> which are small clusters of cells not greater than 0.2&nbsp;mm, or single tumor cells, or a cluster of fewer than 200 cells in a single histologic cross-section, whether detected by routine histology or [[immunohistochemistry]]; </div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>:* N0(i+) : Isolated Tumor Cell clusters (ITC),<ref name=Stanford/> which are small clusters of cells not greater than 0.2&nbsp;mm, or single tumor cells, or a cluster of fewer than 200 cells in a single histologic cross-section, whether detected by routine histology or [[immunohistochemistry]]; </div></td></tr>
</table>
Mikael Häggström
https://patholines.org/index.php?title=Template:Breast_cancer_staging&diff=4866&oldid=prev
Mikael Häggström: Moved to lymph node biopsy or excision
2022-02-24T15:02:30Z
<p>Moved to lymph node biopsy or excision</p>
<table class="diff diff-contentalign-left" data-mw="interface">
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<col class="diff-marker" />
<col class="diff-content" />
<tr class="diff-title" lang="en">
<td colspan="2" style="background-color: #fff; color: #222; text-align: center;">← Older revision</td>
<td colspan="2" style="background-color: #fff; color: #222; text-align: center;">Revision as of 15:02, 24 February 2022</td>
</tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l23" >Line 23:</td>
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<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>====Regional Lymph Nodes (N)====</div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>====Regional Lymph Nodes (N)====</div></td></tr>
<tr><td class='diff-marker'>−</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>Lymph '''N'''ode:{{#ifeq:{{PAGENAME}}|Invasive lobular carcinoma|&nbsp;When lymph nodes are submitted together with a biopsy or excision of a suspected or previously confirmed invasive lobular carcinoma (<del class="diffchange diffchange-inline">or even just </del>invasive carcinoma with lobular features), <del class="diffchange diffchange-inline">generally put the lymph node specimen through H&E processing at a relative rush. If </del>you don't see any involvement on the H&E stain, order immunostain for CK AE1/AE3 in order to visualize otherwise occult lymph node involvement<del class="diffchange diffchange-inline">. The rushing of the lymph node samples allows you to have the immunostained slides by a similar time as the rest of the case</del>.<ref name="pmid12610108">{{cite journal| author=Chandler IP, Oommen R, Lawson CW| title=Invasive lobular carcinoma and cytokeratin immunohistochemistry: an audit. | journal=J Clin Pathol | year= 2003 | volume= 56 | issue= 3 | pages= 240 | pmid=12610108 | doi=10.1136/jcp.56.3.240 | pmc=1769908 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12610108 }} </ref><P>|&nbsp;}}The lymph node values depend on the number, size and location of breast cancer cell deposits in various regional lymph nodes, such as the armpit (axillary lymph nodes), the collar area (supraclavicular lymph nodes), and inside the chest (internal mammary lymph nodes.)<ref name="pmid3347753">{{cite journal |vauthors=Scatarige JC, Fishman EK, Zinreich ES, Brem RF, Almaraz R |title=Internal mammary lymphadenopathy in breast carcinoma: CT appraisal of anatomic distribution |journal=Radiology |volume=167 |issue=1 |pages=89–91 |date=April 1988 |pmid=3347753 |doi= 10.1148/radiology.167.1.3347753|url=}}</ref><ref name="pmid2217975">{{cite journal |vauthors=Scatarige JC, Boxen I, Smathers RL |title=Internal mammary lymphadenopathy: imaging of a vital lymphatic pathway in breast cancer |journal=Radiographics |volume=10 |issue=5 |pages=857–70 |date=September 1990 |pmid=2217975 |doi= 10.1148/radiographics.10.5.2217975|url=}}</ref> Each stage is as follows:<ref name=Alkabban2019/></div></td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>Lymph '''N'''ode:{{#ifeq:{{PAGENAME}}|Invasive lobular carcinoma|&nbsp;When lymph nodes are submitted together with a biopsy or excision of a suspected or previously confirmed invasive lobular carcinoma (<ins class="diffchange diffchange-inline">but not necessarily </ins>invasive carcinoma with lobular features), <ins class="diffchange diffchange-inline">and </ins>you don't see any involvement on the H&E stain, order immunostain for CK AE1/AE3 in order to visualize otherwise occult lymph node involvement.<ref name="pmid12610108">{{cite journal| author=Chandler IP, Oommen R, Lawson CW| title=Invasive lobular carcinoma and cytokeratin immunohistochemistry: an audit. | journal=J Clin Pathol | year= 2003 | volume= 56 | issue= 3 | pages= 240 | pmid=12610108 | doi=10.1136/jcp.56.3.240 | pmc=1769908 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12610108 }} </ref><P>|&nbsp;}}The lymph node values depend on the number, size and location of breast cancer cell deposits in various regional lymph nodes, such as the armpit (axillary lymph nodes), the collar area (supraclavicular lymph nodes), and inside the chest (internal mammary lymph nodes.)<ref name="pmid3347753">{{cite journal |vauthors=Scatarige JC, Fishman EK, Zinreich ES, Brem RF, Almaraz R |title=Internal mammary lymphadenopathy in breast carcinoma: CT appraisal of anatomic distribution |journal=Radiology |volume=167 |issue=1 |pages=89–91 |date=April 1988 |pmid=3347753 |doi= 10.1148/radiology.167.1.3347753|url=}}</ref><ref name="pmid2217975">{{cite journal |vauthors=Scatarige JC, Boxen I, Smathers RL |title=Internal mammary lymphadenopathy: imaging of a vital lymphatic pathway in breast cancer |journal=Radiographics |volume=10 |issue=5 |pages=857–70 |date=September 1990 |pmid=2217975 |doi= 10.1148/radiographics.10.5.2217975|url=}}</ref> Each stage is as follows:<ref name=Alkabban2019/></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>*N0: There is some nuance to the official definitions for N0 disease, which includes:</div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>*N0: There is some nuance to the official definitions for N0 disease, which includes:</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>:* N0(i+) : Isolated Tumor Cell clusters (ITC),<ref name=Stanford/> which are small clusters of cells not greater than 0.2&nbsp;mm, or single tumor cells, or a cluster of fewer than 200 cells in a single histologic cross-section, whether detected by routine histology or [[immunohistochemistry]]; </div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>:* N0(i+) : Isolated Tumor Cell clusters (ITC),<ref name=Stanford/> which are small clusters of cells not greater than 0.2&nbsp;mm, or single tumor cells, or a cluster of fewer than 200 cells in a single histologic cross-section, whether detected by routine histology or [[immunohistochemistry]]; </div></td></tr>
</table>
Mikael Häggström
https://patholines.org/index.php?title=Template:Breast_cancer_staging&diff=4864&oldid=prev
Mikael Häggström: /* Regional Lymph Nodes (N) */ Or lobular features
2022-02-24T14:38:56Z
<p><span dir="auto"><span class="autocomment">Regional Lymph Nodes (N): </span> Or lobular features</span></p>
<table class="diff diff-contentalign-left" data-mw="interface">
<col class="diff-marker" />
<col class="diff-content" />
<col class="diff-marker" />
<col class="diff-content" />
<tr class="diff-title" lang="en">
<td colspan="2" style="background-color: #fff; color: #222; text-align: center;">← Older revision</td>
<td colspan="2" style="background-color: #fff; color: #222; text-align: center;">Revision as of 14:38, 24 February 2022</td>
</tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l23" >Line 23:</td>
<td colspan="2" class="diff-lineno">Line 23:</td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>====Regional Lymph Nodes (N)====</div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>====Regional Lymph Nodes (N)====</div></td></tr>
<tr><td class='diff-marker'>−</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>Lymph '''N'''ode:{{#ifeq:{{PAGENAME}}|Invasive lobular carcinoma|&nbsp;When lymph nodes are submitted together with a biopsy or excision of a suspected or previously confirmed invasive lobular carcinoma, generally put the lymph node specimen through H&E processing at a relative rush. If you don't see any involvement on the H&E stain, order immunostain for CK AE1/AE3 in order to visualize otherwise occult lymph node involvement. The rushing of the lymph node samples allows you to have the immunostained slides by a similar time as the rest of the case.<ref name="pmid12610108">{{cite journal| author=Chandler IP, Oommen R, Lawson CW| title=Invasive lobular carcinoma and cytokeratin immunohistochemistry: an audit. | journal=J Clin Pathol | year= 2003 | volume= 56 | issue= 3 | pages= 240 | pmid=12610108 | doi=10.1136/jcp.56.3.240 | pmc=1769908 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12610108 }} </ref><P>|&nbsp;}}The lymph node values depend on the number, size and location of breast cancer cell deposits in various regional lymph nodes, such as the armpit (axillary lymph nodes), the collar area (supraclavicular lymph nodes), and inside the chest (internal mammary lymph nodes.)<ref name="pmid3347753">{{cite journal |vauthors=Scatarige JC, Fishman EK, Zinreich ES, Brem RF, Almaraz R |title=Internal mammary lymphadenopathy in breast carcinoma: CT appraisal of anatomic distribution |journal=Radiology |volume=167 |issue=1 |pages=89–91 |date=April 1988 |pmid=3347753 |doi= 10.1148/radiology.167.1.3347753|url=}}</ref><ref name="pmid2217975">{{cite journal |vauthors=Scatarige JC, Boxen I, Smathers RL |title=Internal mammary lymphadenopathy: imaging of a vital lymphatic pathway in breast cancer |journal=Radiographics |volume=10 |issue=5 |pages=857–70 |date=September 1990 |pmid=2217975 |doi= 10.1148/radiographics.10.5.2217975|url=}}</ref> Each stage is as follows:<ref name=Alkabban2019/></div></td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>Lymph '''N'''ode:{{#ifeq:{{PAGENAME}}|Invasive lobular carcinoma|&nbsp;When lymph nodes are submitted together with a biopsy or excision of a suspected or previously confirmed invasive lobular carcinoma <ins class="diffchange diffchange-inline">(or even just invasive carcinoma with lobular features)</ins>, generally put the lymph node specimen through H&E processing at a relative rush. If you don't see any involvement on the H&E stain, order immunostain for CK AE1/AE3 in order to visualize otherwise occult lymph node involvement. The rushing of the lymph node samples allows you to have the immunostained slides by a similar time as the rest of the case.<ref name="pmid12610108">{{cite journal| author=Chandler IP, Oommen R, Lawson CW| title=Invasive lobular carcinoma and cytokeratin immunohistochemistry: an audit. | journal=J Clin Pathol | year= 2003 | volume= 56 | issue= 3 | pages= 240 | pmid=12610108 | doi=10.1136/jcp.56.3.240 | pmc=1769908 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12610108 }} </ref><P>|&nbsp;}}The lymph node values depend on the number, size and location of breast cancer cell deposits in various regional lymph nodes, such as the armpit (axillary lymph nodes), the collar area (supraclavicular lymph nodes), and inside the chest (internal mammary lymph nodes.)<ref name="pmid3347753">{{cite journal |vauthors=Scatarige JC, Fishman EK, Zinreich ES, Brem RF, Almaraz R |title=Internal mammary lymphadenopathy in breast carcinoma: CT appraisal of anatomic distribution |journal=Radiology |volume=167 |issue=1 |pages=89–91 |date=April 1988 |pmid=3347753 |doi= 10.1148/radiology.167.1.3347753|url=}}</ref><ref name="pmid2217975">{{cite journal |vauthors=Scatarige JC, Boxen I, Smathers RL |title=Internal mammary lymphadenopathy: imaging of a vital lymphatic pathway in breast cancer |journal=Radiographics |volume=10 |issue=5 |pages=857–70 |date=September 1990 |pmid=2217975 |doi= 10.1148/radiographics.10.5.2217975|url=}}</ref> Each stage is as follows:<ref name=Alkabban2019/></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>*N0: There is some nuance to the official definitions for N0 disease, which includes:</div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>*N0: There is some nuance to the official definitions for N0 disease, which includes:</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>:* N0(i+) : Isolated Tumor Cell clusters (ITC),<ref name=Stanford/> which are small clusters of cells not greater than 0.2&nbsp;mm, or single tumor cells, or a cluster of fewer than 200 cells in a single histologic cross-section, whether detected by routine histology or [[immunohistochemistry]]; </div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>:* N0(i+) : Isolated Tumor Cell clusters (ITC),<ref name=Stanford/> which are small clusters of cells not greater than 0.2&nbsp;mm, or single tumor cells, or a cluster of fewer than 200 cells in a single histologic cross-section, whether detected by routine histology or [[immunohistochemistry]]; </div></td></tr>
</table>
Mikael Häggström
https://patholines.org/index.php?title=Template:Breast_cancer_staging&diff=4314&oldid=prev
Mikael Häggström: /* Regional Lymph Nodes (N) */ P
2021-12-04T19:22:33Z
<p><span dir="auto"><span class="autocomment">Regional Lymph Nodes (N): </span> P</span></p>
<table class="diff diff-contentalign-left" data-mw="interface">
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<col class="diff-content" />
<col class="diff-marker" />
<col class="diff-content" />
<tr class="diff-title" lang="en">
<td colspan="2" style="background-color: #fff; color: #222; text-align: center;">← Older revision</td>
<td colspan="2" style="background-color: #fff; color: #222; text-align: center;">Revision as of 19:22, 4 December 2021</td>
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<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>====Regional Lymph Nodes (N)====</div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>====Regional Lymph Nodes (N)====</div></td></tr>
<tr><td class='diff-marker'>−</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>Lymph '''N'''ode:{{#ifeq:{{PAGENAME}}|Invasive lobular carcinoma| When lymph nodes are submitted together with a biopsy or excision of a suspected or previously confirmed invasive lobular carcinoma, generally put the lymph node specimen through H&E processing at a relative rush. If you don't see any involvement on the H&E stain, order immunostain for CK AE1/AE3 in order to visualize otherwise occult lymph node involvement. The rushing of the lymph node samples allows you to have the immunostained slides by a similar time as the rest of the case.<ref name="pmid12610108">{{cite journal| author=Chandler IP, Oommen R, Lawson CW| title=Invasive lobular carcinoma and cytokeratin immunohistochemistry: an audit. | journal=J Clin Pathol | year= 2003 | volume= 56 | issue= 3 | pages= 240 | pmid=12610108 | doi=10.1136/jcp.56.3.240 | pmc=1769908 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12610108 }} </ref></div></td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>Lymph '''N'''ode:{{#ifeq:{{PAGENAME}}|Invasive lobular carcinoma|<ins class="diffchange diffchange-inline">&nbsp;</ins>When lymph nodes are submitted together with a biopsy or excision of a suspected or previously confirmed invasive lobular carcinoma, generally put the lymph node specimen through H&E processing at a relative rush. If you don't see any involvement on the H&E stain, order immunostain for CK AE1/AE3 in order to visualize otherwise occult lymph node involvement. The rushing of the lymph node samples allows you to have the immunostained slides by a similar time as the rest of the case.<ref name="pmid12610108">{{cite journal| author=Chandler IP, Oommen R, Lawson CW| title=Invasive lobular carcinoma and cytokeratin immunohistochemistry: an audit. | journal=J Clin Pathol | year= 2003 | volume= 56 | issue= 3 | pages= 240 | pmid=12610108 | doi=10.1136/jcp.56.3.240 | pmc=1769908 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12610108 }} </ref><ins class="diffchange diffchange-inline"><P></ins>|&nbsp;}}The lymph node values depend on the number, size and location of breast cancer cell deposits in various regional lymph nodes, such as the armpit (axillary lymph nodes), the collar area (supraclavicular lymph nodes), and inside the chest (internal mammary lymph nodes.)<ref name="pmid3347753">{{cite journal |vauthors=Scatarige JC, Fishman EK, Zinreich ES, Brem RF, Almaraz R |title=Internal mammary lymphadenopathy in breast carcinoma: CT appraisal of anatomic distribution |journal=Radiology |volume=167 |issue=1 |pages=89–91 |date=April 1988 |pmid=3347753 |doi= 10.1148/radiology.167.1.3347753|url=}}</ref><ref name="pmid2217975">{{cite journal |vauthors=Scatarige JC, Boxen I, Smathers RL |title=Internal mammary lymphadenopathy: imaging of a vital lymphatic pathway in breast cancer |journal=Radiographics |volume=10 |issue=5 |pages=857–70 |date=September 1990 |pmid=2217975 |doi= 10.1148/radiographics.10.5.2217975|url=}}</ref> Each stage is as follows:<ref name=Alkabban2019/></div></td></tr>
<tr><td class='diff-marker'>−</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div> </div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>−</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>|&nbsp;}}The lymph node values depend on the number, size and location of breast cancer cell deposits in various regional lymph nodes, such as the armpit (axillary lymph nodes), the collar area (supraclavicular lymph nodes), and inside the chest (internal mammary lymph nodes.)<ref name="pmid3347753">{{cite journal |vauthors=Scatarige JC, Fishman EK, Zinreich ES, Brem RF, Almaraz R |title=Internal mammary lymphadenopathy in breast carcinoma: CT appraisal of anatomic distribution |journal=Radiology |volume=167 |issue=1 |pages=89–91 |date=April 1988 |pmid=3347753 |doi= 10.1148/radiology.167.1.3347753|url=}}</ref><ref name="pmid2217975">{{cite journal |vauthors=Scatarige JC, Boxen I, Smathers RL |title=Internal mammary lymphadenopathy: imaging of a vital lymphatic pathway in breast cancer |journal=Radiographics |volume=10 |issue=5 |pages=857–70 |date=September 1990 |pmid=2217975 |doi= 10.1148/radiographics.10.5.2217975|url=}}</ref> Each stage is as follows:<ref name=Alkabban2019/></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>*N0: There is some nuance to the official definitions for N0 disease, which includes:</div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>*N0: There is some nuance to the official definitions for N0 disease, which includes:</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>:* N0(i+) : Isolated Tumor Cell clusters (ITC),<ref name=Stanford/> which are small clusters of cells not greater than 0.2&nbsp;mm, or single tumor cells, or a cluster of fewer than 200 cells in a single histologic cross-section, whether detected by routine histology or [[immunohistochemistry]]; </div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>:* N0(i+) : Isolated Tumor Cell clusters (ITC),<ref name=Stanford/> which are small clusters of cells not greater than 0.2&nbsp;mm, or single tumor cells, or a cluster of fewer than 200 cells in a single histologic cross-section, whether detected by routine histology or [[immunohistochemistry]]; </div></td></tr>
</table>
Mikael Häggström
https://patholines.org/index.php?title=Template:Breast_cancer_staging&diff=4312&oldid=prev
Mikael Häggström: /* Regional Lymph Nodes (N) */ Corrected
2021-12-04T19:21:05Z
<p><span dir="auto"><span class="autocomment">Regional Lymph Nodes (N): </span> Corrected</span></p>
<table class="diff diff-contentalign-left" data-mw="interface">
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<col class="diff-content" />
<col class="diff-marker" />
<col class="diff-content" />
<tr class="diff-title" lang="en">
<td colspan="2" style="background-color: #fff; color: #222; text-align: center;">← Older revision</td>
<td colspan="2" style="background-color: #fff; color: #222; text-align: center;">Revision as of 19:21, 4 December 2021</td>
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<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>====Regional Lymph Nodes (N)====</div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>====Regional Lymph Nodes (N)====</div></td></tr>
<tr><td class='diff-marker'>−</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>Lymph '''N'''ode:{{#ifeq:{{PAGENAME}}| When lymph nodes are submitted together with a biopsy or excision of a suspected or previously confirmed invasive lobular carcinoma, generally put the lymph node specimen through H&E processing at a relative rush. If you don't see any involvement on the H&E stain, order immunostain for CK AE1/AE3 in order to visualize otherwise occult lymph node involvement. The rushing of the lymph node samples allows you to have the immunostained slides by a similar time as the rest of the case.<ref name="pmid12610108">{{cite journal| author=Chandler IP, Oommen R, Lawson CW| title=Invasive lobular carcinoma and cytokeratin immunohistochemistry: an audit. | journal=J Clin Pathol | year= 2003 | volume= 56 | issue= 3 | pages= 240 | pmid=12610108 | doi=10.1136/jcp.56.3.240 | pmc=1769908 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12610108 }} </ref></div></td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>Lymph '''N'''ode:{{#ifeq:{{PAGENAME}}<ins class="diffchange diffchange-inline">|Invasive lobular carcinoma</ins>| When lymph nodes are submitted together with a biopsy or excision of a suspected or previously confirmed invasive lobular carcinoma, generally put the lymph node specimen through H&E processing at a relative rush. If you don't see any involvement on the H&E stain, order immunostain for CK AE1/AE3 in order to visualize otherwise occult lymph node involvement. The rushing of the lymph node samples allows you to have the immunostained slides by a similar time as the rest of the case.<ref name="pmid12610108">{{cite journal| author=Chandler IP, Oommen R, Lawson CW| title=Invasive lobular carcinoma and cytokeratin immunohistochemistry: an audit. | journal=J Clin Pathol | year= 2003 | volume= 56 | issue= 3 | pages= 240 | pmid=12610108 | doi=10.1136/jcp.56.3.240 | pmc=1769908 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12610108 }} </ref></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|&nbsp;}}The lymph node values depend on the number, size and location of breast cancer cell deposits in various regional lymph nodes, such as the armpit (axillary lymph nodes), the collar area (supraclavicular lymph nodes), and inside the chest (internal mammary lymph nodes.)<ref name="pmid3347753">{{cite journal |vauthors=Scatarige JC, Fishman EK, Zinreich ES, Brem RF, Almaraz R |title=Internal mammary lymphadenopathy in breast carcinoma: CT appraisal of anatomic distribution |journal=Radiology |volume=167 |issue=1 |pages=89–91 |date=April 1988 |pmid=3347753 |doi= 10.1148/radiology.167.1.3347753|url=}}</ref><ref name="pmid2217975">{{cite journal |vauthors=Scatarige JC, Boxen I, Smathers RL |title=Internal mammary lymphadenopathy: imaging of a vital lymphatic pathway in breast cancer |journal=Radiographics |volume=10 |issue=5 |pages=857–70 |date=September 1990 |pmid=2217975 |doi= 10.1148/radiographics.10.5.2217975|url=}}</ref> Each stage is as follows:<ref name=Alkabban2019/></div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|&nbsp;}}The lymph node values depend on the number, size and location of breast cancer cell deposits in various regional lymph nodes, such as the armpit (axillary lymph nodes), the collar area (supraclavicular lymph nodes), and inside the chest (internal mammary lymph nodes.)<ref name="pmid3347753">{{cite journal |vauthors=Scatarige JC, Fishman EK, Zinreich ES, Brem RF, Almaraz R |title=Internal mammary lymphadenopathy in breast carcinoma: CT appraisal of anatomic distribution |journal=Radiology |volume=167 |issue=1 |pages=89–91 |date=April 1988 |pmid=3347753 |doi= 10.1148/radiology.167.1.3347753|url=}}</ref><ref name="pmid2217975">{{cite journal |vauthors=Scatarige JC, Boxen I, Smathers RL |title=Internal mammary lymphadenopathy: imaging of a vital lymphatic pathway in breast cancer |journal=Radiographics |volume=10 |issue=5 |pages=857–70 |date=September 1990 |pmid=2217975 |doi= 10.1148/radiographics.10.5.2217975|url=}}</ref> Each stage is as follows:<ref name=Alkabban2019/></div></td></tr>
</table>
Mikael Häggström
https://patholines.org/index.php?title=Template:Breast_cancer_staging&diff=4308&oldid=prev
Mikael Häggström: /* Regional Lymph Nodes (N) */ Wording
2021-12-04T19:19:11Z
<p><span dir="auto"><span class="autocomment">Regional Lymph Nodes (N): </span> Wording</span></p>
<table class="diff diff-contentalign-left" data-mw="interface">
<col class="diff-marker" />
<col class="diff-content" />
<col class="diff-marker" />
<col class="diff-content" />
<tr class="diff-title" lang="en">
<td colspan="2" style="background-color: #fff; color: #222; text-align: center;">← Older revision</td>
<td colspan="2" style="background-color: #fff; color: #222; text-align: center;">Revision as of 19:19, 4 December 2021</td>
</tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l23" >Line 23:</td>
<td colspan="2" class="diff-lineno">Line 23:</td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>====Regional Lymph Nodes (N)====</div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>====Regional Lymph Nodes (N)====</div></td></tr>
<tr><td class='diff-marker'>−</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>Lymph '''N'''ode&nbsp;<del class="diffchange diffchange-inline">– </del>The lymph node values depend on the number, size and location of breast cancer cell deposits in various regional lymph nodes, such as the armpit (axillary lymph nodes), the collar area (supraclavicular lymph nodes), and inside the chest (internal mammary lymph nodes.)<ref name="pmid3347753">{{cite journal |vauthors=Scatarige JC, Fishman EK, Zinreich ES, Brem RF, Almaraz R |title=Internal mammary lymphadenopathy in breast carcinoma: CT appraisal of anatomic distribution |journal=Radiology |volume=167 |issue=1 |pages=89–91 |date=April 1988 |pmid=3347753 |doi= 10.1148/radiology.167.1.3347753|url=}}</ref><ref name="pmid2217975">{{cite journal |vauthors=Scatarige JC, Boxen I, Smathers RL |title=Internal mammary lymphadenopathy: imaging of a vital lymphatic pathway in breast cancer |journal=Radiographics |volume=10 |issue=5 |pages=857–70 |date=September 1990 |pmid=2217975 |doi= 10.1148/radiographics.10.5.2217975|url=}}</ref> <del class="diffchange diffchange-inline">{{#ifeq:{{PAGENAME}}|Invasive lobular carcinoma|Small axillary lymph node metastases from an invasive lobular carcinoma of the breast can be notoriously difficult to detect on routine haematoxylin and eosin (H&E) staining. Since August 2001, it has been our departmental policy to carry out immunohistochemistry using a broad spectrum antikeratin antibody (AE1/AE3)| &nbsp;}} </del>Each stage is as follows:<ref name=Alkabban2019/></div></td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>Lymph '''N'''ode<ins class="diffchange diffchange-inline">:{{#ifeq:{{PAGENAME}}| When lymph nodes are submitted together with a biopsy or excision of a suspected or previously confirmed invasive lobular carcinoma, generally put the lymph node specimen through H&E processing at a relative rush. If you don't see any involvement on the H&E stain, order immunostain for CK AE1/AE3 in order to visualize otherwise occult lymph node involvement. The rushing of the lymph node samples allows you to have the immunostained slides by a similar time as the rest of the case.<ref name="pmid12610108">{{cite journal| author=Chandler IP, Oommen R, Lawson CW| title=Invasive lobular carcinoma and cytokeratin immunohistochemistry: an audit. | journal=J Clin Pathol | year= 2003 | volume= 56 | issue= 3 | pages= 240 | pmid=12610108 | doi=10.1136/jcp.56.3.240 | pmc=1769908 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12610108 }} </ref></ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div> </div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins class="diffchange diffchange-inline">|</ins>&nbsp;<ins class="diffchange diffchange-inline">}}</ins>The lymph node values depend on the number, size and location of breast cancer cell deposits in various regional lymph nodes, such as the armpit (axillary lymph nodes), the collar area (supraclavicular lymph nodes), and inside the chest (internal mammary lymph nodes.)<ref name="pmid3347753">{{cite journal |vauthors=Scatarige JC, Fishman EK, Zinreich ES, Brem RF, Almaraz R |title=Internal mammary lymphadenopathy in breast carcinoma: CT appraisal of anatomic distribution |journal=Radiology |volume=167 |issue=1 |pages=89–91 |date=April 1988 |pmid=3347753 |doi= 10.1148/radiology.167.1.3347753|url=}}</ref><ref name="pmid2217975">{{cite journal |vauthors=Scatarige JC, Boxen I, Smathers RL |title=Internal mammary lymphadenopathy: imaging of a vital lymphatic pathway in breast cancer |journal=Radiographics |volume=10 |issue=5 |pages=857–70 |date=September 1990 |pmid=2217975 |doi= 10.1148/radiographics.10.5.2217975|url=}}</ref> Each stage is as follows:<ref name=Alkabban2019/></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>*N0: There is some nuance to the official definitions for N0 disease, which includes:</div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>*N0: There is some nuance to the official definitions for N0 disease, which includes:</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>:* N0(i+) : Isolated Tumor Cell clusters (ITC),<ref name=Stanford/> which are small clusters of cells not greater than 0.2&nbsp;mm, or single tumor cells, or a cluster of fewer than 200 cells in a single histologic cross-section, whether detected by routine histology or [[immunohistochemistry]]; </div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>:* N0(i+) : Isolated Tumor Cell clusters (ITC),<ref name=Stanford/> which are small clusters of cells not greater than 0.2&nbsp;mm, or single tumor cells, or a cluster of fewer than 200 cells in a single histologic cross-section, whether detected by routine histology or [[immunohistochemistry]]; </div></td></tr>
</table>
Mikael Häggström
https://patholines.org/index.php?title=Template:Breast_cancer_staging&diff=4306&oldid=prev
Mikael Häggström: /* Regional Lymph Nodes (N) */ Template
2021-12-04T19:09:27Z
<p><span dir="auto"><span class="autocomment">Regional Lymph Nodes (N): </span> Template</span></p>
<table class="diff diff-contentalign-left" data-mw="interface">
<col class="diff-marker" />
<col class="diff-content" />
<col class="diff-marker" />
<col class="diff-content" />
<tr class="diff-title" lang="en">
<td colspan="2" style="background-color: #fff; color: #222; text-align: center;">← Older revision</td>
<td colspan="2" style="background-color: #fff; color: #222; text-align: center;">Revision as of 19:09, 4 December 2021</td>
</tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l23" >Line 23:</td>
<td colspan="2" class="diff-lineno">Line 23:</td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>====Regional Lymph Nodes (N)====</div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>====Regional Lymph Nodes (N)====</div></td></tr>
<tr><td class='diff-marker'>−</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>Lymph '''N'''ode&nbsp;– The lymph node values depend on the number, size and location of breast cancer cell deposits in various regional lymph nodes, such as the armpit (axillary lymph nodes), the collar area (supraclavicular lymph nodes), and inside the chest (internal mammary lymph nodes.)<ref name="pmid3347753">{{cite journal |vauthors=Scatarige JC, Fishman EK, Zinreich ES, Brem RF, Almaraz R |title=Internal mammary lymphadenopathy in breast carcinoma: CT appraisal of anatomic distribution |journal=Radiology |volume=167 |issue=1 |pages=89–91 |date=April 1988 |pmid=3347753 |doi= 10.1148/radiology.167.1.3347753|url=}}</ref><ref name="pmid2217975">{{cite journal |vauthors=Scatarige JC, Boxen I, Smathers RL |title=Internal mammary lymphadenopathy: imaging of a vital lymphatic pathway in breast cancer |journal=Radiographics |volume=10 |issue=5 |pages=857–70 |date=September 1990 |pmid=2217975 |doi= 10.1148/radiographics.10.5.2217975|url=}}</ref> Each stage is as follows:<ref name=Alkabban2019/></div></td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>Lymph '''N'''ode&nbsp;– The lymph node values depend on the number, size and location of breast cancer cell deposits in various regional lymph nodes, such as the armpit (axillary lymph nodes), the collar area (supraclavicular lymph nodes), and inside the chest (internal mammary lymph nodes.)<ref name="pmid3347753">{{cite journal |vauthors=Scatarige JC, Fishman EK, Zinreich ES, Brem RF, Almaraz R |title=Internal mammary lymphadenopathy in breast carcinoma: CT appraisal of anatomic distribution |journal=Radiology |volume=167 |issue=1 |pages=89–91 |date=April 1988 |pmid=3347753 |doi= 10.1148/radiology.167.1.3347753|url=}}</ref><ref name="pmid2217975">{{cite journal |vauthors=Scatarige JC, Boxen I, Smathers RL |title=Internal mammary lymphadenopathy: imaging of a vital lymphatic pathway in breast cancer |journal=Radiographics |volume=10 |issue=5 |pages=857–70 |date=September 1990 |pmid=2217975 |doi= 10.1148/radiographics.10.5.2217975|url=}}</ref> <ins class="diffchange diffchange-inline">{{#ifeq:{{PAGENAME}}|Invasive lobular carcinoma|Small axillary lymph node metastases from an invasive lobular carcinoma of the breast can be notoriously difficult to detect on routine haematoxylin and eosin (H&E) staining. Since August 2001, it has been our departmental policy to carry out immunohistochemistry using a broad spectrum antikeratin antibody (AE1/AE3)| &nbsp;}} </ins>Each stage is as follows:<ref name=Alkabban2019/></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>*N0: There is some nuance to the official definitions for N0 disease, which includes:</div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>*N0: There is some nuance to the official definitions for N0 disease, which includes:</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>:* N0(i+) : Isolated Tumor Cell clusters (ITC),<ref name=Stanford/> which are small clusters of cells not greater than 0.2&nbsp;mm, or single tumor cells, or a cluster of fewer than 200 cells in a single histologic cross-section, whether detected by routine histology or [[immunohistochemistry]]; </div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>:* N0(i+) : Isolated Tumor Cell clusters (ITC),<ref name=Stanford/> which are small clusters of cells not greater than 0.2&nbsp;mm, or single tumor cells, or a cluster of fewer than 200 cells in a single histologic cross-section, whether detected by routine histology or [[immunohistochemistry]]; </div></td></tr>
</table>
Mikael Häggström
https://patholines.org/index.php?title=Template:Breast_cancer_staging&diff=3834&oldid=prev
Mikael Häggström: /* Staging */ +Image
2021-09-13T23:28:06Z
<p><span dir="auto"><span class="autocomment">Staging: </span> +Image</span></p>
<table class="diff diff-contentalign-left" data-mw="interface">
<col class="diff-marker" />
<col class="diff-content" />
<col class="diff-marker" />
<col class="diff-content" />
<tr class="diff-title" lang="en">
<td colspan="2" style="background-color: #fff; color: #222; text-align: center;">← Older revision</td>
<td colspan="2" style="background-color: #fff; color: #222; text-align: center;">Revision as of 23:28, 13 September 2021</td>
</tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l2" >Line 2:</td>
<td colspan="2" class="diff-lineno">Line 2:</td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Stage by the TNM system as follows in sections below.</div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Stage by the TNM system as follows in sections below.</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"></td></tr>
<tr><td class='diff-marker'>−</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>Also, look for any angiolymphatic invasion. If present, check whether it reaches outside the tumor, and if so, how far.<ref name=Stanford>{{cite web|url=http://surgpathcriteria.stanford.edu/breast/infductcabr/grading.html|title=Infiltrating Ductal Carcinoma of the Breast (Carcinoma of No Special Type)|website=Stanford Medical School|accessdate=2019-10-02}}</ref> Give 3 dimensions <del class="diffchange diffchange-inline">or greatest dimension</del>.<ref name=Stanford/></div></td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>Also, look for any angiolymphatic invasion. If present, check whether it reaches outside the tumor, and if so, how far.<ref name=Stanford>{{cite web|url=http://surgpathcriteria.stanford.edu/breast/infductcabr/grading.html|title=Infiltrating Ductal Carcinoma of the Breast (Carcinoma of No Special Type)|website=Stanford Medical School|accessdate=2019-10-02}}</ref> Give <ins class="diffchange diffchange-inline">greatest dimension {{Moderate-begin}},or </ins>3 dimensions<ins class="diffchange diffchange-inline">, generally by adding up the estimated thicknesses of involved slices{{Comprehensive-end}}</ins>.<ref name=Stanford/></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{|class="wikitable"</div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{|class="wikitable"</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|</div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|</div></td></tr>
<tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l9" >Line 9:</td>
<td colspan="2" class="diff-lineno">Line 9:</td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>*TX: inability to assess that site</div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>*TX: inability to assess that site</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>*Tis: [[ductal carcinoma in situ]] (DCIS), [[lobular carcinoma in situ]] (LCIS) or [[Paget's disease of the breast]]</div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>*Tis: [[ductal carcinoma in situ]] (DCIS), [[lobular carcinoma in situ]] (LCIS) or [[Paget's disease of the breast]]</div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">[[File:Measurement of tumor size on two microscopy slides.jpg|thumb|220px|Measurements can be made by marking the tumor on microscopy, and then measuring between the markings, which may overlap between multiple slides as shown.]]</ins></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>*T1: Less than 2 cm</div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>*T1: Less than 2 cm</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>:*T1a: 0.1 to 0.5 cm</div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>:*T1a: 0.1 to 0.5 cm</div></td></tr>
</table>
Mikael Häggström
https://patholines.org/index.php?title=Template:Breast_cancer_staging&diff=457&oldid=prev
Mikael Häggström: subsectioned
2019-10-04T15:05:57Z
<p>subsectioned</p>
<table class="diff diff-contentalign-left" data-mw="interface">
<col class="diff-marker" />
<col class="diff-content" />
<col class="diff-marker" />
<col class="diff-content" />
<tr class="diff-title" lang="en">
<td colspan="2" style="background-color: #fff; color: #222; text-align: center;">← Older revision</td>
<td colspan="2" style="background-color: #fff; color: #222; text-align: center;">Revision as of 15:05, 4 October 2019</td>
</tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l21" >Line 21:</td>
<td colspan="2" class="diff-lineno">Line 21:</td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>:*T4d: [[Inflammatory breast cancer]], a clinical circumstance where typical skin changes involve at least a third of the breast.</div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>:*T4d: [[Inflammatory breast cancer]], a clinical circumstance where typical skin changes involve at least a third of the breast.</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"></td></tr>
<tr><td class='diff-marker'>−</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>===Regional Lymph Nodes (N)===</div></td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins class="diffchange diffchange-inline">=</ins>===Regional Lymph Nodes (N)<ins class="diffchange diffchange-inline">=</ins>===</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Lymph '''N'''ode&nbsp;– The lymph node values depend on the number, size and location of breast cancer cell deposits in various regional lymph nodes, such as the armpit (axillary lymph nodes), the collar area (supraclavicular lymph nodes), and inside the chest (internal mammary lymph nodes.)<ref name="pmid3347753">{{cite journal |vauthors=Scatarige JC, Fishman EK, Zinreich ES, Brem RF, Almaraz R |title=Internal mammary lymphadenopathy in breast carcinoma: CT appraisal of anatomic distribution |journal=Radiology |volume=167 |issue=1 |pages=89–91 |date=April 1988 |pmid=3347753 |doi= 10.1148/radiology.167.1.3347753|url=}}</ref><ref name="pmid2217975">{{cite journal |vauthors=Scatarige JC, Boxen I, Smathers RL |title=Internal mammary lymphadenopathy: imaging of a vital lymphatic pathway in breast cancer |journal=Radiographics |volume=10 |issue=5 |pages=857–70 |date=September 1990 |pmid=2217975 |doi= 10.1148/radiographics.10.5.2217975|url=}}</ref> Each stage is as follows:<ref name=Alkabban2019/></div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Lymph '''N'''ode&nbsp;– The lymph node values depend on the number, size and location of breast cancer cell deposits in various regional lymph nodes, such as the armpit (axillary lymph nodes), the collar area (supraclavicular lymph nodes), and inside the chest (internal mammary lymph nodes.)<ref name="pmid3347753">{{cite journal |vauthors=Scatarige JC, Fishman EK, Zinreich ES, Brem RF, Almaraz R |title=Internal mammary lymphadenopathy in breast carcinoma: CT appraisal of anatomic distribution |journal=Radiology |volume=167 |issue=1 |pages=89–91 |date=April 1988 |pmid=3347753 |doi= 10.1148/radiology.167.1.3347753|url=}}</ref><ref name="pmid2217975">{{cite journal |vauthors=Scatarige JC, Boxen I, Smathers RL |title=Internal mammary lymphadenopathy: imaging of a vital lymphatic pathway in breast cancer |journal=Radiographics |volume=10 |issue=5 |pages=857–70 |date=September 1990 |pmid=2217975 |doi= 10.1148/radiographics.10.5.2217975|url=}}</ref> Each stage is as follows:<ref name=Alkabban2019/></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>*N0: There is some nuance to the official definitions for N0 disease, which includes:</div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>*N0: There is some nuance to the official definitions for N0 disease, which includes:</div></td></tr>
<tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l39" >Line 39:</td>
<td colspan="2" class="diff-lineno">Line 39:</td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>*M1: Distant detectable metastases as determined by classic clinical and radiographic means, and/or metastasis that are histologically larger than 0.2&nbsp;mm.</div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>*M1: Distant detectable metastases as determined by classic clinical and radiographic means, and/or metastasis that are histologically larger than 0.2&nbsp;mm.</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"></td></tr>
<tr><td class='diff-marker'>−</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>===Overall stage===</div></td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins class="diffchange diffchange-inline">=</ins>===Overall stage<ins class="diffchange diffchange-inline">=</ins>===</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>A combination of T, N and M, as follows:<ref name=Alkabban2019/></div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>A combination of T, N and M, as follows:<ref name=Alkabban2019/></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>*Stage 0: Tis</div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>*Stage 0: Tis</div></td></tr>
</table>
Mikael Häggström
https://patholines.org/index.php?title=Template:Breast_cancer_staging&diff=443&oldid=prev
Mikael Häggström: Tabled
2019-10-04T13:47:08Z
<p>Tabled</p>
<table class="diff diff-contentalign-left" data-mw="interface">
<col class="diff-marker" />
<col class="diff-content" />
<col class="diff-marker" />
<col class="diff-content" />
<tr class="diff-title" lang="en">
<td colspan="2" style="background-color: #fff; color: #222; text-align: center;">← Older revision</td>
<td colspan="2" style="background-color: #fff; color: #222; text-align: center;">Revision as of 13:47, 4 October 2019</td>
</tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l1" >Line 1:</td>
<td colspan="2" class="diff-lineno">Line 1:</td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>===Staging===</div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>===Staging===</div></td></tr>
<tr><td class='diff-marker'>−</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>Stage by the TNM system as follows.</div></td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>Stage by the TNM system as follows <ins class="diffchange diffchange-inline">in sections below</ins>.</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Also, look for any angiolymphatic invasion. If present, check whether it reaches outside the tumor, and if so, how far.<ref name=Stanford>{{cite web|url=http://surgpathcriteria.stanford.edu/breast/infductcabr/grading.html|title=Infiltrating Ductal Carcinoma of the Breast (Carcinoma of No Special Type)|website=Stanford Medical School|accessdate=2019-10-02}}</ref> Give 3 dimensions or greatest dimension.<ref name=Stanford/></div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Also, look for any angiolymphatic invasion. If present, check whether it reaches outside the tumor, and if so, how far.<ref name=Stanford>{{cite web|url=http://surgpathcriteria.stanford.edu/breast/infductcabr/grading.html|title=Infiltrating Ductal Carcinoma of the Breast (Carcinoma of No Special Type)|website=Stanford Medical School|accessdate=2019-10-02}}</ref> Give 3 dimensions or greatest dimension.<ref name=Stanford/></div></td></tr>
<tr><td class='diff-marker'>−</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div> </div></td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins class="diffchange diffchange-inline">{|class="wikitable"</ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins class="diffchange diffchange-inline">|</ins></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>====Primary Tumor (T)====</div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>====Primary Tumor (T)====</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>'''T'''umor&nbsp;– Depends on the tumor at the primary site of origin, as follows:<ref name=Alkabban2019>Originally copied from {{cite web|url=https://www.ncbi.nlm.nih.gov/books/NBK482286/|title=Cancer, Breast|author=Fadi M. Alkabban; Troy Ferguson|website=National Center for Biotechnology Information}} Last Update: June 4, 2019. [http://creativecommons.org/licenses/by/4.0/ Creative Commons Attribution 4.0 International License]</ref> </div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>'''T'''umor&nbsp;– Depends on the tumor at the primary site of origin, as follows:<ref name=Alkabban2019>Originally copied from {{cite web|url=https://www.ncbi.nlm.nih.gov/books/NBK482286/|title=Cancer, Breast|author=Fadi M. Alkabban; Troy Ferguson|website=National Center for Biotechnology Information}} Last Update: June 4, 2019. [http://creativecommons.org/licenses/by/4.0/ Creative Commons Attribution 4.0 International License]</ref> </div></td></tr>
<tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l44" >Line 44:</td>
<td colspan="2" class="diff-lineno">Line 45:</td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>*Stage II: T2N0, T3N0 T0N1, T1N1, or T2N1</div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>*Stage II: T2N0, T3N0 T0N1, T1N1, or T2N1</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>*Stage III: Invasion into skin and/or ribs, matted lymph nodes, T3N1, T0N2, T1N2, T2N2, T3N2, AnyT N3, T4 any N, locally advanced breast cancer</div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>*Stage III: Invasion into skin and/or ribs, matted lymph nodes, T3N1, T0N2, T1N2, T2N2, T3N2, AnyT N3, T4 any N, locally advanced breast cancer</div></td></tr>
<tr><td class='diff-marker'>−</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>*Stage IV: M1, advanced breast cancer<noinclude></div></td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>*Stage IV: M1, advanced breast cancer</div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins class="diffchange diffchange-inline">|}</ins><noinclude></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{Bottom}}</div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{Bottom}}</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div></noinclude></div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div></noinclude></div></td></tr>
</table>
Mikael Häggström