Difference between revisions of "Template:Hepatocellular adenoma versus carcinoma"
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↑ Bioulac-Sage, Paulette; Sempoux, Christine; Possenti, Laurent; Frulio, Nora; Laumonier, Hervé; Laurent, Christophe; Chiche, Laurence; Frédéric Blanc, Jean; et al. (2013). "Pathological Diagnosis of Hepatocellular Cellular Adenoma according to the Clinical Context
". International Journal of Hepatology 2013: 1–13. doi:. ISSN 2090-3448.
↑ Author: Avani Pendse, M.D., Ph.D.. Liver & intrahepatic bile ducts - Benign / nonneoplastic - Hepatocellular adenoma. Pathology Outlines. Topic Completed: 1 October 2018. Minor changes: 30 September 2020
↑ Chan, Anthony W H; Yu, Shuangni; Yu, Yau-Hei; Tong, Joanna H M; Wang, Lei; Tin, Edith K Y; Chong, Charing C N; Chan, Stephen L; et al. (2016). "Steatotic hepatocellular carcinoma: a variant associated with metabolic factors and late tumour relapse
". Histopathology 69 (6): 971–984. doi:. ISSN 03090167.
↑ Motohashi, Ikuko; Okudaira, Masahiko; Takai, Tomoko; Kaneko, Satoshi; Ikeda, Noriaki (1992). "Morphological differences between hepatocellular carcinoma and hepatocellular carcinomalike lesions
". Hepatology 16 (1): 118–126. doi:. ISSN 02709139.
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===Hepatocellular adenoma versus carcinoma=== | ===Hepatocellular adenoma versus carcinoma=== | ||
[[File:Histopathology of inflammatory hepatocellular adenoma.jpg|thumb|Histopathology of inflammatory hepatocellular adenoma, with inflammatory cells and minor atypia.<ref name="Bioulac-SageSempoux2013">{{cite journal|last1=Bioulac-Sage|first1=Paulette|last2=Sempoux|first2=Christine|last3=Possenti|first3=Laurent|last4=Frulio|first4=Nora|last5=Laumonier|first5=Hervé|last6=Laurent|first6=Christophe|last7=Chiche|first7=Laurence|last8=Frédéric Blanc|first8=Jean|last9=Saric|first9=Jean|last10=Trillaud|first10=Hervé|last11=Le Bail|first11=Brigitte|last12=Balabaud|first12=Charles|title=Pathological Diagnosis of Hepatocellular Cellular Adenoma according to the Clinical Context|journal=International Journal of Hepatology|volume=2013|year=2013|pages=1–13|issn=2090-3448|doi=10.1155/2013/253261}}</ref>]] | [[File:Histopathology of inflammatory hepatocellular adenoma.jpg|thumb|Histopathology of inflammatory hepatocellular adenoma, with inflammatory cells and minor atypia.<ref name="Bioulac-SageSempoux2013">{{cite journal|last1=Bioulac-Sage|first1=Paulette|last2=Sempoux|first2=Christine|last3=Possenti|first3=Laurent|last4=Frulio|first4=Nora|last5=Laumonier|first5=Hervé|last6=Laurent|first6=Christophe|last7=Chiche|first7=Laurence|last8=Frédéric Blanc|first8=Jean|last9=Saric|first9=Jean|last10=Trillaud|first10=Hervé|last11=Le Bail|first11=Brigitte|last12=Balabaud|first12=Charles|title=Pathological Diagnosis of Hepatocellular Cellular Adenoma according to the Clinical Context|journal=International Journal of Hepatology|volume=2013|year=2013|pages=1–13|issn=2090-3448|doi=10.1155/2013/253261}}</ref>]] | ||
| − | A '''hepatocellular adenoma''', in contrast, has a well-defined border between the lesion and background liver, and is composed of hepatocytes with less significant cytologic atypia.<ref>{{cite web|url=https://www.pathologyoutlines.com/topic/livertumorhepatocellularadenoma.html|title=Liver & intrahepatic bile ducts - Benign / nonneoplastic - Hepatocellular adenoma|author=Author: Avani Pendse, M.D., Ph.D.|website=Pathology Outlines}} Topic Completed: 1 October 2018. Minor changes: 30 September 2020</ref> | + | A '''hepatocellular adenoma''', in contrast to a carcinoma, has a well-defined border between the lesion and background liver, and is composed of hepatocytes with less significant cytologic atypia.<ref>{{cite web|url=https://www.pathologyoutlines.com/topic/livertumorhepatocellularadenoma.html|title=Liver & intrahepatic bile ducts - Benign / nonneoplastic - Hepatocellular adenoma|author=Author: Avani Pendse, M.D., Ph.D.|website=Pathology Outlines}} Topic Completed: 1 October 2018. Minor changes: 30 September 2020</ref> |
Both hepatocellular adenoma and well-differentiated hepatocellular carcinoma may display: | Both hepatocellular adenoma and well-differentiated hepatocellular carcinoma may display: | ||
*'''Steatosis''': A steatotic hepatocellular carcinoma is a common variant, found most commonly in small, well-differentiated tumors.<ref name="ChanYu2016">{{cite journal|last1=Chan|first1=Anthony W H|last2=Yu|first2=Shuangni|last3=Yu|first3=Yau-Hei|last4=Tong|first4=Joanna H M|last5=Wang|first5=Lei|last6=Tin|first6=Edith K Y|last7=Chong|first7=Charing C N|last8=Chan|first8=Stephen L|last9=Wong|first9=Grace L H|last10=Wong|first10=Vincent W S|last11=Chan|first11=Henry L Y|last12=Lai|first12=Paul B S|last13=To|first13=Ka-Fai|title=Steatotic hepatocellular carcinoma: a variant associated with metabolic factors and late tumour relapse|journal=Histopathology|volume=69|issue=6|year=2016|pages=971–984|issn=03090167|doi=10.1111/his.13029}}</ref> | *'''Steatosis''': A steatotic hepatocellular carcinoma is a common variant, found most commonly in small, well-differentiated tumors.<ref name="ChanYu2016">{{cite journal|last1=Chan|first1=Anthony W H|last2=Yu|first2=Shuangni|last3=Yu|first3=Yau-Hei|last4=Tong|first4=Joanna H M|last5=Wang|first5=Lei|last6=Tin|first6=Edith K Y|last7=Chong|first7=Charing C N|last8=Chan|first8=Stephen L|last9=Wong|first9=Grace L H|last10=Wong|first10=Vincent W S|last11=Chan|first11=Henry L Y|last12=Lai|first12=Paul B S|last13=To|first13=Ka-Fai|title=Steatotic hepatocellular carcinoma: a variant associated with metabolic factors and late tumour relapse|journal=Histopathology|volume=69|issue=6|year=2016|pages=971–984|issn=03090167|doi=10.1111/his.13029}}</ref> | ||
*'''Portal triads''', which commonly persist in well-differentiated hepatocellular carcinomas.<ref name="MotohashiOkudaira1992">{{cite journal|last1=Motohashi|first1=Ikuko|last2=Okudaira|first2=Masahiko|last3=Takai|first3=Tomoko|last4=Kaneko|first4=Satoshi|last5=Ikeda|first5=Noriaki|title=Morphological differences between hepatocellular carcinoma and hepatocellular carcinomalike lesions|journal=Hepatology|volume=16|issue=1|year=1992|pages=118–126|issn=02709139|doi=10.1002/hep.1840160120}}</ref> | *'''Portal triads''', which commonly persist in well-differentiated hepatocellular carcinomas.<ref name="MotohashiOkudaira1992">{{cite journal|last1=Motohashi|first1=Ikuko|last2=Okudaira|first2=Masahiko|last3=Takai|first3=Tomoko|last4=Kaneko|first4=Satoshi|last5=Ikeda|first5=Noriaki|title=Morphological differences between hepatocellular carcinoma and hepatocellular carcinomalike lesions|journal=Hepatology|volume=16|issue=1|year=1992|pages=118–126|issn=02709139|doi=10.1002/hep.1840160120}}</ref> | ||
Revision as of 10:49, 11 February 2021
Hepatocellular adenoma versus carcinoma
Histopathology of inflammatory hepatocellular adenoma, with inflammatory cells and minor atypia.[1]
A hepatocellular adenoma, in contrast to a carcinoma, has a well-defined border between the lesion and background liver, and is composed of hepatocytes with less significant cytologic atypia.[2]
Both hepatocellular adenoma and well-differentiated hepatocellular carcinoma may display:
- Steatosis: A steatotic hepatocellular carcinoma is a common variant, found most commonly in small, well-differentiated tumors.[3]
- Portal triads, which commonly persist in well-differentiated hepatocellular carcinomas.[4]
