Difference between revisions of "Template:Microscopic evaluation of neoadjuvant invasive cancer"

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}}</noinclude>{{Edit|Template:Microscopic evaluation of neoadjuvant invasive cancer}}</br>In neoadjuvant cases (patient has received chemotherapy, endocrine therapy and/or radiotherapy before the excision), perform:
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</noinclude>In neoadjuvant cases (patient has received chemotherapy, endocrine therapy and/or radiotherapy before the excision), perform:
 
 
*Measurement of the '''tumor bed''' which generally manifests as a fibroelastic area.
 
*Measurement of the '''tumor bed''' which generally manifests as a fibroelastic area.
 
*Classification of '''residual cancer''', for which there are multiple systems, mainly ''Residual Cancer Burden'' (RCB)<ref group=notes>A calculator and explanations for calculating RCB is found at: http://www3.mdanderson.org/app/medcalc/index.cfm?pagename=jsconvert3</ref> and the American Joint Committee on Cancer post-neoadjuvant therapy staging system (yAJCC).<ref name="pmid28577078">{{cite journal| author=Campbell JI, Yau C, Krass P, Moore D, Carey LA, Au A | display-authors=etal| title=Comparison of residual cancer burden, American Joint Committee on Cancer staging and pathologic complete response in breast cancer after neoadjuvant chemotherapy: results from the I-SPY 1 TRIAL (CALGB 150007/150012; ACRIN 6657). | journal=Breast Cancer Res Treat | year= 2017 | volume= 165 | issue= 1 | pages= 181-191 | pmid=28577078 | doi=10.1007/s10549-017-4303-8 | pmc=5653207 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=28577078  }} </ref><noinclude>
 
*Classification of '''residual cancer''', for which there are multiple systems, mainly ''Residual Cancer Burden'' (RCB)<ref group=notes>A calculator and explanations for calculating RCB is found at: http://www3.mdanderson.org/app/medcalc/index.cfm?pagename=jsconvert3</ref> and the American Joint Committee on Cancer post-neoadjuvant therapy staging system (yAJCC).<ref name="pmid28577078">{{cite journal| author=Campbell JI, Yau C, Krass P, Moore D, Carey LA, Au A | display-authors=etal| title=Comparison of residual cancer burden, American Joint Committee on Cancer staging and pathologic complete response in breast cancer after neoadjuvant chemotherapy: results from the I-SPY 1 TRIAL (CALGB 150007/150012; ACRIN 6657). | journal=Breast Cancer Res Treat | year= 2017 | volume= 165 | issue= 1 | pages= 181-191 | pmid=28577078 | doi=10.1007/s10549-017-4303-8 | pmc=5653207 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=28577078  }} </ref><noinclude>
 
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Revision as of 11:30, 17 September 2021

Author: Mikael Häggström [note 1]
edit
In neoadjuvant cases (patient has received chemotherapy, endocrine therapy and/or radiotherapy before the excision), perform:

  • Measurement of the tumor bed which generally manifests as a fibroelastic area.
  • Classification of residual cancer, for which there are multiple systems, mainly Residual Cancer Burden (RCB)[notes 1] and the American Joint Committee on Cancer post-neoadjuvant therapy staging system (yAJCC).[1]

Notes

  1. A calculator and explanations for calculating RCB is found at: http://www3.mdanderson.org/app/medcalc/index.cfm?pagename=jsconvert3
  1. For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.

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