Difference between revisions of "Template:Overlap of squamous-cell and basal-cell carcinoma"

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Yet, a high prevalence means a relatively high incidence of borderline cases, with main forms being:
 
Yet, a high prevalence means a relatively high incidence of borderline cases, with main forms being:
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File:BCC with squamous cell metaplasia.jpg|'''Basal-cell carcinoma with squamous cell metaplasia''' or metatypical (squamoid) basal-cell carcinoma.
 
File:BCC with squamous cell metaplasia.jpg|'''Basal-cell carcinoma with squamous cell metaplasia''' or metatypical (squamoid) basal-cell carcinoma.
 
File:Histopathology of basaloid squamous cell carcinoma.png|'''Basaloid squamous-cell carcinoma''', in this case showing a biplastic pattern with conventional dysplastic squamous surface component associated with basaloid elements (arrow heads) and conventional squamous cell carcinoma intimately associated with basaloid component (arrow).<ref>{{cite journal|last1=El-Mofty|first1=SK.|title=Histopathologic risk factors in oral and oropharyngeal squamous cell carcinoma variants: An update with special reference to HPV-related carcinomas|journal=Medicina Oral Patología Oral y Cirugia Bucal|year=2014|pages=e377–e385|issn=16986946|doi=10.4317/medoral.20184}}<br>License: CC BY 2.5</ref>
 
File:Histopathology of basaloid squamous cell carcinoma.png|'''Basaloid squamous-cell carcinoma''', in this case showing a biplastic pattern with conventional dysplastic squamous surface component associated with basaloid elements (arrow heads) and conventional squamous cell carcinoma intimately associated with basaloid component (arrow).<ref>{{cite journal|last1=El-Mofty|first1=SK.|title=Histopathologic risk factors in oral and oropharyngeal squamous cell carcinoma variants: An update with special reference to HPV-related carcinomas|journal=Medicina Oral Patología Oral y Cirugia Bucal|year=2014|pages=e377–e385|issn=16986946|doi=10.4317/medoral.20184}}<br>License: CC BY 2.5</ref>

Revision as of 08:45, 17 May 2022

Author: Mikael Häggström [note 1]

edit

Yet, a high prevalence means a relatively high incidence of borderline cases, with main forms being:

In unclear cases, the most useful immunohistochemistry marker appears to be MOC-31, which essentially always stains metatypical basal-cell carcinomas but not basaloid squamous-cell carcinomas.[2] UEA-1 appears to be the second most useful marker, staining almost all basaloid squamous-cell carcinomas but only a few metatypical basal-cell carcinomas.[2]

Notes

  1. For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.

Main page

References

  1. El-Mofty, SK. (2014). "Histopathologic risk factors in oral and oropharyngeal squamous cell carcinoma variants: An update with special reference to HPV-related carcinomas ". Medicina Oral Patología Oral y Cirugia Bucal: e377–e385. doi:10.4317/medoral.20184. ISSN 16986946. 
    License: CC BY 2.5
  2. 2.0 2.1 Webb, David V.; Mentrikoski, Mark J.; Verduin, Lindsey; Brill, Louis B.; Wick, Mark R. (2015). "Basal cell carcinoma vs basaloid squamous cell carcinoma of the skin: an immunohistochemical reappraisal ". Annals of Diagnostic Pathology 19 (2): 70–75. doi:10.1016/j.anndiagpath.2015.01.004. ISSN 10929134. 

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