Difference between revisions of "Thyroid"

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*[[Hyperthyroidism]]
 
*[[Hyperthyroidism]]
  
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{{Fixation - standard}} Fix all thyroids at least overnight to avoid artifactual nuclear atypia.<ref name=chicago>{{cite web|url=https://voices.uchicago.edu/grosspathology/head-neck/thyroid/#primary-column|title=Gross Pathology Manual By The University of Chicago Department of Pathology}} Updated 2-14-19 NAC.</ref>
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{{Fixation - standard}} Fix all thyroids at least overnight to avoid artifactual nuclear atypia.<ref name=chicago2>{{cite web|url=https://voices.uchicago.edu/grosspathology/head-neck/thyroid/#primary-column|title=Gross Pathology Manual By The University of Chicago Department of Pathology}} Updated 2-14-19 NAC.</ref>
 
{{Fixation - general notes}}
 
{{Fixation - general notes}}
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{{Gross processing of thyroid}}
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==Gross processing==
 
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*'''Weigh'''<ref name=chicago/>
 
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*'''Measure''' each lobe and isthmus in 3 dimensions, respectively.<ref name=chicago/>
 
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*'''Ink''' outer surface,<ref name=chicago/> at least if malignancy is suspected.<ref>{{Stora utskärningen}}</ref>:{{Ink note}}
 
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<gallery>
 
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File:Grossing of hemithyroidectomy.svg|Hemithyroidecomy (lobe + isthmus) or lobectomy, including completion thyroidectomies: Use separate colors over the cut surface and the outer “capsular” surface.<ref group="notes" name="coloring">Separate coloring allows to distinguish the thyroid margin (continuous with the other lobe) from the peripheral margin (towards soft tissues).</ref>
 
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File:How to not gross hemithyroidectomy.svg|None of the outer “capsular” surface should be inked like the cut surface.<ref group="notes" name="coloring"/>
 
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File:Grossing of thyroidectomy with isthmus.svg|Intact total thyroidectomy: Separate colors for each lobe and the isthmus.
 
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File:Grossing of thyroidectomy without isthmus.svg|If no appreciable isthmus, Separate colors for each lobe.
 
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</gallery>
 
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Serially '''section''' the specimen at 3-4mm intervals,<ref>{{cite web|url=https://www.rcpa.edu.au/Manuals/Macroscopic-Cut-Up-Manual/Endocrine/Thyroid|title=THYROID|website=Royal College of pathologists of Australia|accessdate=2019-12-17}}</ref> such as follows:<ref name=chicago/>
 
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<gallery>
 
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File:Sectioning of hemithyroidectomy.svg|Hemithyroidecomy (lobe + isthmus) or lobectomy: Include isthmic orange margins in your transverse sections.
 
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File:Sectioning of thyroidectomy with isthmus.svg|Intact total thyroidectomy: Transverse lobe sections and sagittal isthmus sections
 
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File:Sectioning of thyroidectomy without isthmus.svg|Short/inconspicious isthmus: The isthmus can be included in the transverse sections.
 
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</gallery>
 
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{{Gross processing}}
 
 
{{Bottom}}
 
{{Bottom}}

Revision as of 14:04, 9 July 2020

Author: Mikael Häggström [note 1]

Presentations

Fixation

Generally 10% neutral buffered formalin. Fix all thyroids at least overnight to avoid artifactual nuclear atypia.[1]

  See also: General notes on fixation


Template:Gross processing of thyroid

Notes

  1. ↑ For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.

Main page

References

  1. ↑ . Gross Pathology Manual By The University of Chicago Department of Pathology. Updated 2-14-19 NAC.

Image sources


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