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Author: Mikael Häggström [note 1]



Generally 10% neutral buffered formalin. Fix all thyroids at least overnight to avoid artifactual nuclear atypia.[1]

  See also: General notes on fixation

Gross processing

  • Weigh[1]
  • Measure each lobe and isthmus in 3 dimensions, respectively.[1]
  • Ink outer surface,[1] at least if malignancy is suspected.[2]:Template:Ink note

Serially section the specimen at 3-4mm intervals,[3] such as follows:[1]

  See also: General notes on gross processing


  1. 1.0 1.1 Separate coloring allows to distinguish the thyroid margin (continuous with the other lobe) from the peripheral margin (towards soft tissues).
  1. For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.

Main page


  1. 1.0 1.1 1.2 1.3 1.4 . Gross Pathology Manual By The University of Chicago Department of Pathology. Updated 2-14-19 NAC.
  2. Monica Dahlgren, Janne Malina, Anna Måsbäck, Otto Ljungberg. Stora utskärningen. KVAST (Swedish Society of Pathology). Retrieved on 2019-09-26.
  3. . THYROID. Royal College of pathologists of Australia. Retrieved on 2019-12-17.

Image sources