Difference between revisions of "Thyroid cytology"

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==Risk stratification==
 
==Risk stratification==
[[File:Cytopathology of papillary thyroid carcinoma.png|thumb|300px|Papillary thyroid carcinoma, with typical features shown. Pap stain.]]
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[[File:Cytopathology of papillary thyroid carcinoma.png|thumb|340px|Papillary thyroid carcinoma, with typical features shown. Pap stain.]]
 
Classify findings as per the Bethesda system:
 
Classify findings as per the Bethesda system:
 
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File:Cytology of benign follicular epithelial cells.jpg|Cytology of benign follicular epithelial cells (Bethesda category II), Pap stain, showing cells with significant nuclear pleomorphism but otherwise insignificant features.
 
File:Cytology of benign follicular epithelial cells.jpg|Cytology of benign follicular epithelial cells (Bethesda category II), Pap stain, showing cells with significant nuclear pleomorphism but otherwise insignificant features.
 
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Revision as of 13:22, 22 August 2022

Author: Mikael Häggström [note 1]

Adequacy

A minimum number of 6 clusters with 10 cells each has been arbitrary established to assume adequacy for a definitive diagnosis.[1] The presence of characteristic cells may still confer a definitive diagnosis, but otherwise, the report will simply state inadequate number of cells.

Risk stratification

Papillary thyroid carcinoma, with typical features shown. Pap stain.

Classify findings as per the Bethesda system:

Bethesda system
Category Description[2] Example report
I Non diagnostic/unsatisfactory
II Benign (colloid and follicular cells) Thyroid aspiration, right upper pole:
Negative for malignant cells.
Clusters of benign follicular epithelial cells and colloid. Findings are consistent with a benign hyperplastic nodule. (Bethesda category II)
III Atypia of undetermined significance (AUS) or follicular lesion of undetermined significance (FLUS) (follicular or lymphoid cells with atypical features) Thyroid aspiration, right mid pole:
Clusters of atypical follicular cells of undetermined significance (Bethesda category III).
IV Follicular nodule/suspicious follicular nodule (cell crowding, micro follicles, dispersed isolated cells, scant colloid)
V Suspicious for malignancy
VI Malignant

Notes

  1. For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.

Main page

References

  1. Michael, Claire W.; Pang, Yijun; Pu, Robert T.; Hasteh, Farnaz; Griffith, Kent A. (2007). "Cellular adequacy for thyroid aspirates prepared by ThinPrep: How many cells are needed? ". Diagnostic Cytopathology 35 (12): 792–797. doi:10.1002/dc.20768. ISSN 87551039. 
  2. "The bethesda system for reporting thyroid cytopathology: interpretation and guidelines in surgical treatment ". Indian Journal of Otolaryngology and Head and Neck Surgery 64 (4): 305–311. December 2012. doi:10.1007/s12070-011-0289-4. PMID 24294568. 

Image sources