Difference between revisions of "Tophus"

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==Microscopy evaluation==
 
==Microscopy evaluation==
 
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File:Uric acid crystals in polarized light.png|Uric acid crystals in polarized light, showing negative [[birefringence]], with yellow color when aligned parallel to the axis of the red compensator, and blue when aligned perpendicularly to it.<ref>{{cite web|url=https://emedicine.medscape.com/article/329958-workup|title=Gout and Pseudogout Workup|author=Bruce M Rothschild|website=Medscape}} Updated: Jun 30, 2020</ref>
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File:Uric acid crystals in polarized light.png|Uric acid crystals in polarized light, showing negative birefringence, with yellow color when aligned parallel to the axis of the red compensator, and blue when aligned perpendicularly to it.<ref>{{cite web|url=https://emedicine.medscape.com/article/329958-workup|title=Gout and Pseudogout Workup|author=Bruce M Rothschild|website=Medscape}} Updated: Jun 30, 2020</ref>
 
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Revision as of 17:54, 23 September 2020

Author: Mikael Häggström [note 1]

Preparation

A tophus specimen should be sent dry to the pathology department, and not be put in formalin.[notes 1] A touch prep can be done initially, and at least if urate crystals remain suspected, the specimen is submitted in 100% alcohol for microscopy evaluation.

Microscopy evaluation

Notes

  1. Formalin dissolves the crystals.
  1. For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.

Main page

References

  1. Bruce M Rothschild. Gout and Pseudogout Workup. Medscape. Updated: Jun 30, 2020

Image sources