Difference between revisions of "Urine cytology"
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− | File:Cytopathology of reactive urothelial changes.png|Reactive urothelial changes, Pap stain, showing urothelial cells with enlarged nuclei but a nucleus-cytoplasm ratio of less than 0.5. There are bacteria, as well as an inflammatory response of neutrophils, providing a cause for the changes. Can be reported as ''"Benign urothelial cells, neutrophils and bacteria"''. | + | File:Cytopathology of reactive urothelial changes.png|'''Reactive urothelial changes''', Pap stain, showing urothelial cells with enlarged nuclei but a nucleus-cytoplasm ratio of less than 0.5. There are bacteria, as well as an inflammatory response of neutrophils, providing a cause for the changes. Can be reported as ''"Benign urothelial cells, neutrophils and bacteria"''. |
− | File:HIgh-Grade Urothelial Carcinoma (28263697589).jpg|High-grade urothelial carcinoma. Cytologic diagnosis of high-grade urothelial carcinoma requires > 10 cells with high N/C ratio, irregular chromatin pattern and hyperchromatic nuclei (Pap stain).<ref name="pmid29278461">{{cite journal| author=Wang Y, Auger M, Kanber Y, Caglar D, Brimo F| title=Implementing The Paris System for Reporting Urinary Cytology results in a decrease in the rate of the "atypical" category and an increase in its prediction of subsequent high-grade urothelial carcinoma. | journal=Cancer Cytopathol | year= 2018 | volume= 126 | issue= 3 | pages= 207-214 | pmid=29278461 | doi=10.1002/cncy.21958 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29278461 }} </ref> | + | File:HIgh-Grade Urothelial Carcinoma (28263697589).jpg|'''High-grade urothelial carcinoma'''. Cytologic diagnosis of high-grade urothelial carcinoma requires > 10 cells with high N/C ratio, irregular chromatin pattern and hyperchromatic nuclei (Pap stain).<ref name="pmid29278461">{{cite journal| author=Wang Y, Auger M, Kanber Y, Caglar D, Brimo F| title=Implementing The Paris System for Reporting Urinary Cytology results in a decrease in the rate of the "atypical" category and an increase in its prediction of subsequent high-grade urothelial carcinoma. | journal=Cancer Cytopathol | year= 2018 | volume= 126 | issue= 3 | pages= 207-214 | pmid=29278461 | doi=10.1002/cncy.21958 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29278461 }} </ref> |
File:Decoy cell cytology.png|Distinguish urothelial carcinoma from '''decoy cells''', which are virally infected epithelial cells (Pap stain). | File:Decoy cell cytology.png|Distinguish urothelial carcinoma from '''decoy cells''', which are virally infected epithelial cells (Pap stain). | ||
File:Urine cytology with red blood cells.jpg|Also report the presence of '''red blood cells''' (here seen compared to benign urothelial cells, Pap stain). | File:Urine cytology with red blood cells.jpg|Also report the presence of '''red blood cells''' (here seen compared to benign urothelial cells, Pap stain). |
Revision as of 12:51, 23 September 2022
Author:
Mikael Häggström [note 1]
Clinical information
It is not necessary to look through more than readily available reports from previous urine cytologies.
Evaluation
Mainly look for:
Reactive urothelial changes, Pap stain, showing urothelial cells with enlarged nuclei but a nucleus-cytoplasm ratio of less than 0.5. There are bacteria, as well as an inflammatory response of neutrophils, providing a cause for the changes. Can be reported as "Benign urothelial cells, neutrophils and bacteria".
High-grade urothelial carcinoma. Cytologic diagnosis of high-grade urothelial carcinoma requires > 10 cells with high N/C ratio, irregular chromatin pattern and hyperchromatic nuclei (Pap stain).[1]
Notes
- ↑ For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.
Main page
References
- ↑ Wang Y, Auger M, Kanber Y, Caglar D, Brimo F (2018). "Implementing The Paris System for Reporting Urinary Cytology results in a decrease in the rate of the "atypical" category and an increase in its prediction of subsequent high-grade urothelial carcinoma. ". Cancer Cytopathol 126 (3): 207-214. doi: . PMID 29278461. Archived from the original. .
- ↑ - Image by Mikael Häggström. Reference: Wojcik EM, Kurtycz DFI, Rosenthal DL (2022). "We'll always have Paris The Paris System for Reporting Urinary Cytology 2022. ". J Am Soc Cytopathol 11 (2): 62-66. doi: . PMID 35094954. Archived from the original. .
Image sources