Epidermoid cyst

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Author: Mikael Häggström [notes 1]
Generally presents as a skin cyst. Also known as epidermal inclusion cyst (EIC) and sebaceous cyst.

Microscopic evaluation

Epidermoid cyst

Typical findings:[1]

  • Stratified squamous epithelium with a granular layer
  • Cyst wall does not contain eccrine glands, sebaceous glands or hair follicles
  • Abundant keratin flakes in cyst lumen
  • Often giant cell granuloma in ruptured cysts, similar to foreign body granuloma

Further workup

Look for signs of cyst rupture, which may manifest as inflammation, including granulomas and microabscesses.

Notes

  1. For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.

Main page

References

  1. V. Claire Vaughan, M.D., Joshua Wisell, M.D.. Skin nonmelanocytic tumor - Cysts - Epidermal (epidermoid) type. pathology Outlines. Topic Completed: 9 May 2019. Revised: 13 December 2019