Keloid
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Author:
Mikael Häggström [note 1]
Contents
Gross processing
| <4 mm | 4 - 8 mm | 9 - 15 mm |
|---|---|---|
|
|
|
|
In table above, each top image shows recommended lines for cutting out slices to be submitted for further processing. Bottom image shows which side of the slice that should be put to microtomy. Dashed lines here mean that either side could be used. Further information: Gross processing of skin excisions
Microscopic evaluation
- Keloid versus hypertrophic scar - Typical findings
| Keloid | Hypertrophic scar | |
|---|---|---|
 |
| |
| Flattening of the overlying epidermis | No | Yes |
| Scarring of the papillary dermis | No | Yes |
| Collagen | Thick hyalinized bundles | Whorl-like or nodular arrangements |
| Vertically oriented blood vessels | Yes | No |
| Prominent disarray of fibrous fascicles/nodules | Yes | No |
| Tongue-like advancing edge underneath normal-appearing epidermis and papillary dermis | Yes | No |
| Horizontal cellular fibrous band in the upper reticular dermis | Yes | No |
| Prominent fascia-like fibrous band | Yes | No |
Notes
- ↑ For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.
Main page
References
- ↑
- . Handläggning av hudprover – provtagningsanvisningar, utskärningsprinciper och snittning (Handling of skin samples - sampling instructions, cutting principles and incision. Swedish Society of Pathology.
- For number of slices and coverage of lesions, as well as including sections from each edge in case of diffuse border. - . Dermatopathology Grossing Guidelines. University of California, Los Angeles. Retrieved on 2019-10-23.
- For microtomy of the most central side at the lesion - "The principles of mohs micrographic surgery for cutaneous neoplasia
- With a "standard histologic examination" that, in addition to the lesion, only includes one section from each side along the longest diameter of the specimen.
- It also shows an example of circular coverage, with equal coverage distance in all four directions.
- The entire specimen may be submitted if the risk of malignancy is high. - . Handläggning av hudprover – provtagningsanvisningar, utskärningsprinciper och snittning (Handling of skin samples - sampling instructions, cutting principles and incision. Swedish Society of Pathology.
Image sources
