Generally 10% neutral buffered formalin.
- See also: General notes on fixation
On this resource, the following formatting is used for comprehensiveness:
- Minimal depth
- (Moderate depth)
- Perform consecutive slicing of the entire specimen.
- Look for signs of liposarcoma: Mainly by firm volumes. Color varies from yellow to white (and firm) depending on the proportion of adipocytic, fibrous and/or myxoid content. Areas of fat necrosis are common in larger lesions. Rarely, infiltrative growth is seen.
- Submit slices from any suspicious parts, or at least one representative slice from the specimen. (A more comprehensive practice is to submit 1 section per centimeter, and 2 sections per cassette.)
- Even absence of hemorrhage or necrosis.
|Mass ((weighing 121 grams)) and measuring 10 x 6,5 x 3,5 cm. ((The surgical margin is intact.)) Cut sections show homogenous yellow color, with no hemorrhage or necrosis. ((The specimen is serially sectioned, and representative sections are submitted for microscopic examination in __ cassettes.))|
- See also: General notes on gross processing
Fibrolipoma is a lipoma with focal areas of large amounts of fibrous tissue.
A sclerotic lipoma is one step further: a predominantly fibrous lesion with focal areas of fat.
If unsure of degree of fibrosis: Simply report as lipoma.
Angiolipoma is a lipoma with abundant capillaries, with hyaline or fibrin (pictured) thrombi.
Myxoid liposarcoma: Hypercellular solid sheets of cells lying back to back, with round cells or primitive cytomorphology.
A pedunculated lipomatous skin tumor may be a pedunculated lipofibroma:
For lipomas: Absence of signs of malignancy.
((Tissue composed of univacuolar fat cells and delicate and inconspicuous fibrous septa.)) No evidence of malignancy.
- See also: General notes on reporting
- Monica Dahlgren, Janne Malina, Anna Måsbäck, Otto Ljungberg (1997-02-13). Lilla utskärningen.
- Andreas F Mavrogenis, Panayiotis J Papagelopoulos (2013-02-01). Soft Tissues: Well-differentiated liposarcoma. Atlas of Genetics and Cytogenetics in Oncology and Haematology.
- Pathology Department at NU Hospital Group, Sweden, 2019-2020.
- . Lipoma. Gross Pathology Manual - By The University of Chicago Department of Pathology. Retrieved on 2020-08-26.
- . Lipoma Variant: Fibrolipoma. Stanford University School of Medicine. Retrieved on 2020-02-10.
- Vijay Shankar. Soft tissue - Adipose tissue tumors - Lipoma and variants - Angiolipoma. Pathology Outlines. Topic Completed: 1 August 2012. Minor changes: 20 March 2019
- Michael R. Clay, M.D.. Liposarcoma. PathologyOutlines. Topic Completed: 1 November 2017. Minor changes: 11 May 2021
- Michael R. Clay. Soft tissue - Adipose tissue - Myxoid liposarcoma. PathologyOutlines. Topic Completed: 1 January 2018. Revised: 20 March 2019