Mikael Häggström [note 1]
As per Adrenal tumors
Architecture can be nested (zellballen), trabecular or solid arrangement of tumor cells. Sustentacular cells may be seen surrounding nests, as rather spindly cells.
For a diagnosis of pheochromocytoma, look for any adverse histopathologic features such as vascular or capsular invasion, diffuse growth pattern, necrosis, increased mitotic activity or atypical mitotic figures.
|Right adrenal gland, resection:|
Adrenal pheochromocytoma (3.0 cm tumor).
Surgical margins are negative for neoplasia.
(Optionally: Comment: This adrenal pheochromocytoma exhibits no adverse histopathologic features such as vascular or capsular invasion, diffuse growth pattern, necrosis, increased mitotic activity or atypical mitotic figures. Nonetheless, metastatic potential is difficult to predict based on histologic parameters.)
- ↑ For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.
- ↑ Katherine A. Lehman, B.S., Debra L. Zynger, M.D.. Adrenal gland & paraganglia - Pheochromocytoma / paraganglioma - Pheochromocytoma. Pathology Outlines. Topic Completed: 20 August 2021. Minor changes: 20 August 2021