Proteinaceous material in Bowman's space

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Author: Mikael Häggström [note 1]

Proteinaceous material in Bowman's space.

Proteinaceous material in Bowman's space is unspecific. It is present in about 5% of people aged over 60 years.[1]

Gross processing

As per Kidney.

Microscopic evaluation

Collagenous material in hypertensive nephropathy.
  • Look for a collagenous appearance, with may indicate hypertensive nephropathy.[2]


If no indication of particular disease, it may optionally be reported as:

Proteinaceous material in Bowman's space of a few/minority/majority of glomeruli, which is unspecific.


  1. For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.

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  1. Table 4 in: Hodgin, Jeffrey B.; Bitzer, Markus; Wickman, Larysa; Afshinnia, Farsad; Wang, Su Q; O’Connor, Christopher; Yang, Yan; Meadowbrooke, Chrysta; et al. (2015). "Glomerular Aging and Focal Global Glomerulosclerosis: A Podometric Perspective ". Journal of the American Society of Nephrology 26 (12): 3162–3178. doi:10.1681/ASN.2014080752. ISSN 1046-6673. 
  2. Sharma, Rishi; Kamalakar, Surineni; McCarthy, Ellen; Fields, Timothy A.; Gupta, Kamal; Barua, Rajat; Savin, Virginia (2014). "Proteinuria in Hypertensive Nephropathy: A Review ". Open Journal of Nephrology 04 (02): 92–99. doi:10.4236/ojneph.2014.42013. ISSN 2164-2842. 

Image sources