Reactive lymph node
On this resource, the following formatting is used for comprehensiveness:
- Minimal depth
- (Moderate depth)
Grossing as per lymph nodes in general.
An unspecific gross sign of a reactive lymph node is enlargement. Further information: Lymph node
Microscopic signs of reactive lymphadenopathy:
- Paracortical hyperplasia with expansion of paracortical areas by a mixed infiltrate, often having a mottled appearance, and it usually has a concomitant reactive follicular hyperplasia. A T-cell lymphoma should be suspected if there is obliteration or marked diminution of the B-cell cortical region, or highly irregular or hyperchromatic nuclei.
- Unspecific hyperplasia: An unspecific pattern of lymph node enlargement, without atypical cells, in the lymphatic drainage direction from an inflamed area, may be diagnosed as "benign reactive lymph node".
Reactive lymphadenopathy may be reported as:
|((One (1))) reactive lymph node((, negative for metastatic carcinoma)).|