Talk:Lymph nodes

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Definition of an enlarged lymph node

Moved to here since it's not that relevant.

  • By size, where lymphadenopathy in adults is often defined as a short axis of one or more lymph nodes is greater than 10mm.[1][2] However, there is regional variation as detailed in this table:
Upper limit of lymph node sizes in adults
Generally 10 mm[1][2]
Inguinal 10[3] – 20 mm[4]
Pelvis 10 mm for ovoid lymph nodes, 8 mm for rounded[3]
Neck
Generally (non-retropharyngeal) 10 mm[3][5]
Jugulodigastric lymph nodes 11mm[3] or 15 mm[5]
Retropharyngeal 8 mm[5]
  • Lateral retropharyngeal: 5 mm[3]
Mediastinum
Mediastinum, generally 10 mm[3]
Superior mediastinum and high paratracheal 7mm[6]
Low paratracheal and subcarinal 11 mm[6]
Upper abdominal
Retrocrural space 6 mm[7]
Paracardiac 8 mm[7]
Gastrohepatic ligament 8 mm[7]
Upper paraaortic region 9 mm[7]
Portacaval space 10 mm[7]
Porta hepatis 7 mm[7]
Lower paraaortic region 11 mm[7]

Lymphadenopathy of the axillary lymph nodes can be defined as solid nodes measuring more than 15 mm without fatty hilum.[8] Axillary lymph nodes may be normal up to 30 mm if consisting largely of fat.[8]

In children, a short axis of 8 mm can be used.[9] However, inguinal lymph nodes of up to 15 mm and cervical lymph nodes of up to 20 mm are generally normal in children up to age 8–12.[10]

Lymphadenopathy of more than 1.5 cm - 2 cm increases the risk of cancer or granulomatous disease as the cause rather than only inflammation or infection.[11]

  1. 1.0 1.1 Ganeshalingam, Skandadas; Koh, Dow-Mu (2009). "Nodal staging ". Cancer Imaging 9 (1): 104–111. doi:10.1102/1470-7330.2009.0017. ISSN 1470-7330. PMID 20080453. 
  2. 2.0 2.1 Schmidt Júnior, Aurelino Fernandes; Rodrigues, Olavo Ribeiro; Matheus, Roberto Storte; Kim, Jorge Du Ub; Jatene, Fábio Biscegli (2007). "Distribuição, tamanho e número dos linfonodos mediastinais: definições por meio de estudo anatômico ". Jornal Brasileiro de Pneumologia 33 (2): 134–140. doi:10.1590/S1806-37132007000200006. ISSN 1806-3713. PMID 17724531. 
  3. 3.0 3.1 3.2 3.3 3.4 3.5 "Current concepts in lymph node imaging ". Journal of Nuclear Medicine 45 (9): 1509–18. September 2004. PMID 15347718. 
  4. . Assessment of lymphadenopathy. BMJ Best Practice. Retrieved on 2017-03-04. Last updated: Last updated: Feb 16, 2017
  5. 5.0 5.1 5.2 Page 432 in: Luca Saba (2016). Image Principles, Neck, and the Brain . CRC Press. ISBN 9781482216202. 
  6. 6.0 6.1 Sharma, Amita; Fidias, Panos; Hayman, L. Anne; Loomis, Susanne L.; Taber, Katherine H.; Aquino, Suzanne L. (2004). "Patterns of Lymphadenopathy in Thoracic Malignancies ". RadioGraphics 24 (2): 419–434. doi:10.1148/rg.242035075. ISSN 0271-5333. PMID 15026591. Archived from the original. . 
  7. 7.0 7.1 7.2 7.3 7.4 7.5 7.6 Dorfman, R E; Alpern, M B; Gross, B H; Sandler, M A (1991). "Upper abdominal lymph nodes: criteria for normal size determined with CT. ". Radiology 180 (2): 319–322. doi:10.1148/radiology.180.2.2068292. ISSN 0033-8419. PMID 2068292. 
  8. 8.0 8.1 Page 559 in: Wolfgang Dähnert (2011). Radiology Review Manual . Lippincott Williams & Wilkins. ISBN 9781609139438. 
  9. Page 942 in: Richard M. Gore, Marc S. Levine (2010). High Yield Imaging Gastrointestinal HIGH YIELD in Radiology . Elsevier Health Sciences. ISBN 9781455711444. 
  10. Laurence Knott. Generalised Lymphadenopathy. Patient UK. Retrieved on 2017-03-04. Last checked: 24 March 2014
  11. "Lymphadenopathy and malignancy ". American Family Physician 66 (11): 2103–10. December 2002. PMID 12484692.