Lichen sclerosus: Difference between revisions

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==Microscopic evaluation==

[[File:Micrograph of lichen sclerosus.jpg|thumb|Micrograph of extragenital lichen sclerosus: epidermal atrophy, follicular plugging and basal vacuolization, initial homogenization of collagen in the dermis.<ref>{{cite journal|last1=Jędrowiak|first1=Anna|last2=Kobusiewicz|first2=Aleksandra|last3=Trznadel-Grodzka|first3=Ewa|last4=Kaszuba|first4=Andrzej|title=Dermoscopic findings in extragenital lichen sclerosus|journal=Our Dermatology Online|volume=9|issue=2|year=2018|pages=197–199|issn=20819390|doi=10.7241/ourd.20182.24}}<br>- "Figures - available via license: CC BY 4.0"</ref>]]

[[File:Micrograph of lichen sclerosus.jpg|thumb|Micrograph of extragenital lichen sclerosus: epidermal atrophy, follicular plugging and basal vacuolization, and sclerosis with initial homogenization of collagen in the dermis.<ref>{{cite journal|last1=Jędrowiak|first1=Anna|last2=Kobusiewicz|first2=Aleksandra|last3=Trznadel-Grodzka|first3=Ewa|last4=Kaszuba|first4=Andrzej|title=Dermoscopic findings in extragenital lichen sclerosus|journal=Our Dermatology Online|volume=9|issue=2|year=2018|pages=197–199|issn=20819390|doi=10.7241/ourd.20182.24}}<br>- "Figures - available via license: CC BY 4.0"</ref>]]

Findings associated with lichen sclerosus are:<ref name="emed">{{cite web|url=https://emedicine.medscape.com/article/1123316-overview#|title=Lichen Sclerosus|website=EMedicine|author=Lisa K Pappas-Taffer}} Updated: May 17, 2018</ref>

*Hyperkeratosis

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*Sclerosis of the dermis

*Lymphocytes in the dermis

Also look for dysplasia.<ref name="Shelley2006">{{Cite journal | last1 = Shelley | first1 = W. B. | last2 = Shelley | first2 = E. D. | last3 = Amurao | first3 = C. V. | doi = 10.1111/j.1365-4632.2006.02978.x | title = Treatment of lichen sclerosus with antibiotics | journal = International Journal of Dermatology | volume = 45 | issue = 9 | pages = 1104–1106 | year = 2006 | pmid = 16961523| pmc = }}</ref>

Also look for dysplasia,<ref name="Shelley2006">{{Cite journal | last1 = Shelley | first1 = W. B. | last2 = Shelley | first2 = E. D. | last3 = Amurao | first3 = C. V. | doi = 10.1111/j.1365-4632.2006.02978.x | title = Treatment of lichen sclerosus with antibiotics | journal = International Journal of Dermatology | volume = 45 | issue = 9 | pages = 1104–1106 | year = 2006 | pmid = 16961523| pmc = }}</ref> especially in the basal layer, which, depending on location, would confer a diagnosis of [[actinic keratosis]] or [[vulvar intraepithelial neoplasia]].

==Reporting==

Report:

*Presence or absence of lichen sclerosus, ~~as well as any~~ dysplasia.~~<ref name="Shelley2006"/>~~

*Presence or absence of lichen sclerosus

*Optionally, even the absence of dysplasia.

@@ Line 12: / Line 12: @@
 {{Gross processing}}
 ==Microscopic evaluation==
-[[File:Micrograph of lichen sclerosus.jpg|thumb|Micrograph of extragenital lichen sclerosus: epidermal atrophy, follicular plugging and basal vacuolization, initial homogenization of collagen in the dermis.<ref>{{cite journal|last1=Jędrowiak|first1=Anna|last2=Kobusiewicz|first2=Aleksandra|last3=Trznadel-Grodzka|first3=Ewa|last4=Kaszuba|first4=Andrzej|title=Dermoscopic findings in extragenital lichen sclerosus|journal=Our Dermatology Online|volume=9|issue=2|year=2018|pages=197–199|issn=20819390|doi=10.7241/ourd.20182.24}}<br>- "Figures - available via license: CC BY 4.0"</ref>]]
+[[File:Micrograph of lichen sclerosus.jpg|thumb|Micrograph of extragenital lichen sclerosus: epidermal atrophy, follicular plugging and basal vacuolization, and sclerosis with initial homogenization of collagen in the dermis.<ref>{{cite journal|last1=Jędrowiak|first1=Anna|last2=Kobusiewicz|first2=Aleksandra|last3=Trznadel-Grodzka|first3=Ewa|last4=Kaszuba|first4=Andrzej|title=Dermoscopic findings in extragenital lichen sclerosus|journal=Our Dermatology Online|volume=9|issue=2|year=2018|pages=197–199|issn=20819390|doi=10.7241/ourd.20182.24}}<br>- "Figures - available via license: CC BY 4.0"</ref>]]
 Findings associated with lichen sclerosus are:<ref name="emed">{{cite web|url=https://emedicine.medscape.com/article/1123316-overview#|title=Lichen Sclerosus|website=EMedicine|author=Lisa K Pappas-Taffer}} Updated: May 17, 2018</ref>
 *Hyperkeratosis
@@ Line 18: / Line 18: @@
 *Sclerosis of the dermis
 *Lymphocytes in the dermis
-Also look for dysplasia.<ref name="Shelley2006">{{Cite journal | last1 = Shelley | first1 = W. B. | last2 = Shelley | first2 = E. D. | last3 = Amurao | first3 = C. V. | doi = 10.1111/j.1365-4632.2006.02978.x | title = Treatment of lichen sclerosus with antibiotics | journal = International Journal of Dermatology | volume = 45 | issue = 9 | pages = 1104–1106 | year = 2006 | pmid =  16961523| pmc = }}</ref>
+Also look for dysplasia,<ref name="Shelley2006">{{Cite journal | last1 = Shelley | first1 = W. B. | last2 = Shelley | first2 = E. D. | last3 = Amurao | first3 = C. V. | doi = 10.1111/j.1365-4632.2006.02978.x | title = Treatment of lichen sclerosus with antibiotics | journal = International Journal of Dermatology | volume = 45 | issue = 9 | pages = 1104–1106 | year = 2006 | pmid =  16961523| pmc = }}</ref> especially in the basal layer, which, depending on location, would confer a diagnosis of [[actinic keratosis]] or [[vulvar intraepithelial neoplasia]].
 ==Reporting==
 Report:
-*Presence or absence of lichen sclerosus, as well as any dysplasia.<ref name="Shelley2006"/>
+*Presence or absence of lichen sclerosus
+*Optionally, even the absence of dysplasia.
 {{Reporting}}
 {{Bottom}}

Lichen sclerosus: Difference between revisions

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